Table 2. Summary of statistical tests... | Rockefeller University Press

Table 2.

Summary of statistical tests for F₀, F_SA, F_SA+F₀, F_SA/F₀, F_SA/(F_SA + F₀), and t₃ per MHC isoform

Statistical test	MHC	F₀	F_SA	F_SA + F₀	F_SA/F₀	F_SA/(F_SA + F₀)	t₃
Main effect	I	0.0022	--	6.87e−4	--	--	--
F-statistic		9.00	--	8.83	--	--	--
Active versus High [Ca²⁺] Fatigue		0.015	--	0.024	--	--	--
Active versus Low [Ca²⁺] Fatigue		0.0019	--	5.37e−4	--	--	--
High versus Low [Ca²⁺] Fatigue		0.39	--	0.36	--	--	--

Main effect	IIA	2.32e−4	3.37e−4	< 1e−7	< 1e−7	< 1e−7	0.017
F-statistic		22.44	15.91	38.08	131.10	185.28	8.11
Active versus High [Ca²⁺] Fatigue		1.60e−6	1.32e−4	4.31e−4	< 1e−7	< 1e−7	1.88e−4
Active versus Low [Ca²⁺] Fatigue		< 1e−7	0.43	< 1e−7	< 1e−7	< 1e−7	0.35
High versus Low [Ca²⁺] Fatigue		0.015	0.16	2.13e−5	0.107	0.11	0.55

Main effect	IIX	4.74e−6	0.092	1.36e−4	1.12e−4	1.79e−05	0.30
F-statistic		33.63	3.23	12.15	34.03	46.13	1.65
Active versus High [Ca²⁺] Fatigue		0.0032	--	0.0576	2.21e−6	< 1e−7	--
Active versus Low [Ca²⁺] Fatigue		< 1e−7	--	8.24e−5	< 1e−7	< 1e−7	--
High versus Low [Ca²⁺] Fatigue		0.024	--	0.043	5.44e−05	1.72e−4	--

Main effect	IIB	3.39e−5	0.0027	< 1e−7	< 1e−7	< 1e−7	0.0035
F-statistic		33.46	12.01	30.47	85.11	101.09	9.69
Active versus High [Ca²⁺] Fatigue		0.0032	0.15	0.0080	< 1e−7	< 1e−7	0.95
Active versus Low [Ca²⁺] Fatigue		< 1e−7	0.0040	< 1e−7	< 1e−7	< 1e−7	1.69e−4
High versus Low [Ca²⁺] Fatigue		1.22e−4	2.49e−6	6.74e−5	3.15e−07	1.06e−6	1.37e−4

Statistical test	MHC	F₀	F_SA	F_SA + F₀	F_SA/F₀	F_SA/(F_SA + F₀)	t₃
Main effect	I	0.0022	--	6.87e−4	--	--	--
F-statistic		9.00	--	8.83	--	--	--
Active versus High [Ca²⁺] Fatigue		0.015	--	0.024	--	--	--
Active versus Low [Ca²⁺] Fatigue		0.0019	--	5.37e−4	--	--	--
High versus Low [Ca²⁺] Fatigue		0.39	--	0.36	--	--	--

Main effect	IIA	2.32e−4	3.37e−4	< 1e−7	< 1e−7	< 1e−7	0.017
F-statistic		22.44	15.91	38.08	131.10	185.28	8.11
Active versus High [Ca²⁺] Fatigue		1.60e−6	1.32e−4	4.31e−4	< 1e−7	< 1e−7	1.88e−4
Active versus Low [Ca²⁺] Fatigue		< 1e−7	0.43	< 1e−7	< 1e−7	< 1e−7	0.35
High versus Low [Ca²⁺] Fatigue		0.015	0.16	2.13e−5	0.107	0.11	0.55

Main effect	IIX	4.74e−6	0.092	1.36e−4	1.12e−4	1.79e−05	0.30
F-statistic		33.63	3.23	12.15	34.03	46.13	1.65
Active versus High [Ca²⁺] Fatigue		0.0032	--	0.0576	2.21e−6	< 1e−7	--
Active versus Low [Ca²⁺] Fatigue		< 1e−7	--	8.24e−5	< 1e−7	< 1e−7	--
High versus Low [Ca²⁺] Fatigue		0.024	--	0.043	5.44e−05	1.72e−4	--

Main effect	IIB	3.39e−5	0.0027	< 1e−7	< 1e−7	< 1e−7	0.0035
F-statistic		33.46	12.01	30.47	85.11	101.09	9.69
Active versus High [Ca²⁺] Fatigue		0.0032	0.15	0.0080	< 1e−7	< 1e−7	0.95
Active versus Low [Ca²⁺] Fatigue		< 1e−7	0.0040	< 1e−7	< 1e−7	< 1e−7	1.69e−4
High versus Low [Ca²⁺] Fatigue		1.22e−4	2.49e−6	6.74e−5	3.15e−07	1.06e−6	1.37e−4

Main effects and F-statistics values derived from the linear mixed model are reported for each test. If the resulting P value for the main effect reached threshold (α = 0.05), Tukey’s post hoc tests were performed to determine pairwise comparison differences between the three experimental conditions. Significant differences are indicated in bold.

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