Table 1.

Postulated experimental causes of variability, grouped as correlated between-experiment (affecting μa and μi similarly in each experiment), uncorrelated between-experiment (affecting μa and μi independently in each experiment), or within-experiment (affecting σa and/or σi)

Between experimentWithin experiment
​ Correlated Uncorrelated ​ 
Missing or erroneous LJP correction ✓✓ ✗ ✗ 
Uncontrollable redox potentials ✓ 
Voltage-control errors ✓ ✓ ✓ 
Voltage protocol ✓ ✓ ✗ 
Analysis method ✗ ✓ ✓ 
Bath and pipette solutions ✗ ✓ 
Temperature ✗ 
Time since rupture 
Stretch ✗ ✗ 
Culture conditions and passage number 
Endogenous currents 
Regulation 
Between experimentWithin experiment
​ Correlated Uncorrelated ​ 
Missing or erroneous LJP correction ✓✓ ✗ ✗ 
Uncontrollable redox potentials ✓ 
Voltage-control errors ✓ ✓ ✓ 
Voltage protocol ✓ ✓ ✗ 
Analysis method ✗ ✓ ✓ 
Bath and pipette solutions ✗ ✓ 
Temperature ✗ 
Time since rupture 
Stretch ✗ ✗ 
Culture conditions and passage number 
Endogenous currents 
Regulation 

Characterized as strongly likely (✓✓), likely (✓), possible (?), or unlikely (✗) to contribute to the different types of variability in measurements of μa and μi.

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