Table 1.

Postulated experimental causes of variability, grouped as correlated between-experiment (affecting μa and μi similarly in each experiment), uncorrelated between-experiment (affecting μa and μi independently in each experiment), or within-experiment (affecting σa and/or σi)

​Between experimentWithin experiment
​ Correlated Uncorrelated ​ 
Missing or erroneous LJP correction ✓✓ ✗ ✗ 
Uncontrollable redox potentials ? ? ✓ 
Voltage-control errors ✓ ✓ ✓ 
Voltage protocol ✓ ✓ ✗ 
Analysis method ✗ ✓ ✓ 
Bath and pipette solutions ✗ ✓ ? 
Temperature ? ✗ ? 
Time since rupture ? ? ? 
Stretch ✗ ✗ ? 
Culture conditions and passage number ? ? ? 
Endogenous currents ? ? ? 
Regulation ? ? ? 

Characterized as strongly likely (✓✓), likely (✓), possible (?), or unlikely (✗) to contribute to the different types of variability in measurements of μa and μi.

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