Baseline characteristics of patients included in the study, stratified by presence of anti-IFN-α2 and/or anti-IFN-ω auto-Abs
| Variables . | Total n = 209 . | Positive n = 14 . | Negative n = 195 . | P value . |
|---|---|---|---|---|
| Age, median (IQR) | 57 (45–70) | 75 (58–80) | 56 (44–67) | <0.001 |
| Sex | ||||
| Male, n (%) | 130 (62.2) | 10 (71.4) | 120 (61.5) | 0.461 |
| Female, n (%) | 79 (37.8) | 4 (28.6) | 75 (38.5) | |
| Comorbidities | ||||
| Hypertension, n (%) | 117 (55.9) | 6 (42.8) | 111 (56.9) | 0.306 |
| Diabetes mellitus, n (%) | 75 (35.8) | 4 (28.5) | 71 (36.4) | 0.555 |
| Obesity, n (%) | 56 (26.7) | 1 (7.1) | 55 (28.2) | 0.086 |
| Chronic kidney disease, n (%) | 17 (8.1) | 3 (21.4) | 14 (7.1) | 0.060 |
| Chronic heart disease, n (%) | 11 (5.2) | 4 (28.5) | 7 (3.5) | <0.001 |
| COPD, n (%) | 9 (4.3) | 1 (7.1) | 8 (4.1) | 0.588 |
| Cancer, n (%) | 4 (1.9) | 0 | 4 (2.0) | 0.588 |
| Variables . | Total n = 209 . | Positive n = 14 . | Negative n = 195 . | P value . |
|---|---|---|---|---|
| Age, median (IQR) | 57 (45–70) | 75 (58–80) | 56 (44–67) | <0.001 |
| Sex | ||||
| Male, n (%) | 130 (62.2) | 10 (71.4) | 120 (61.5) | 0.461 |
| Female, n (%) | 79 (37.8) | 4 (28.6) | 75 (38.5) | |
| Comorbidities | ||||
| Hypertension, n (%) | 117 (55.9) | 6 (42.8) | 111 (56.9) | 0.306 |
| Diabetes mellitus, n (%) | 75 (35.8) | 4 (28.5) | 71 (36.4) | 0.555 |
| Obesity, n (%) | 56 (26.7) | 1 (7.1) | 55 (28.2) | 0.086 |
| Chronic kidney disease, n (%) | 17 (8.1) | 3 (21.4) | 14 (7.1) | 0.060 |
| Chronic heart disease, n (%) | 11 (5.2) | 4 (28.5) | 7 (3.5) | <0.001 |
| COPD, n (%) | 9 (4.3) | 1 (7.1) | 8 (4.1) | 0.588 |
| Cancer, n (%) | 4 (1.9) | 0 | 4 (2.0) | 0.588 |
Continuous variables were compared using the Student’s t test. Categorical variables were compared using the chi-square test or Fisher’s exact test when appropriate. IQR: interquartile range; COPD: chronic obstructive pulmonary disease.