Table 1.

Orientations and relative angle changes of the four conformational states of AdiC

θ1 Exθ2 Eoθ3 Ioθ4 Ix
Crystallographya 93.8° 83.6° 71.7° 95.3° 
Polarization (BFb, Agm2+90° ± 5.3° 88.7° ± 6.7° 77.4° ± 9.3° 90° ± 5.3° 
Polarization (BFb, Arg+90° ± 4.7° 87.8° ± 7.2° 76.6° ± 9.0° 90° ± 4.5° 
Polarization (MFc, Arg+90° ± 4.6° 89.0° ± 5.5° 79.9° ± 7.3° 90° ± 4.1° 
 φ1 Ex φ2 Eo φ3 Io φ4 Ix 
Crystallographya −1.89° 20.9° 27.5° 38.7° 
Polarization (BFb, Agm2+0° ± 4.5° 17.9° ± 6.3° 27.2° ± 9.3° 40.5° ± 10° 
Polarization (BFb, Arg+0° ± 4.0° 16.6° ± 7.2° 26.6° ± 10° 38.5° ± 11° 
Polarization (MFc, Arg+0° ± 3.9° 13.7° ± 4.8° 22.7° ± 6.7° 39.5° ± 7.5° 
θ1 Exθ2 Eoθ3 Ioθ4 Ix
Crystallographya 93.8° 83.6° 71.7° 95.3° 
Polarization (BFb, Agm2+90° ± 5.3° 88.7° ± 6.7° 77.4° ± 9.3° 90° ± 5.3° 
Polarization (BFb, Arg+90° ± 4.7° 87.8° ± 7.2° 76.6° ± 9.0° 90° ± 4.5° 
Polarization (MFc, Arg+90° ± 4.6° 89.0° ± 5.5° 79.9° ± 7.3° 90° ± 4.1° 
 φ1 Ex φ2 Eo φ3 Io φ4 Ix 
Crystallographya −1.89° 20.9° 27.5° 38.7° 
Polarization (BFb, Agm2+0° ± 4.5° 17.9° ± 6.3° 27.2° ± 9.3° 40.5° ± 10° 
Polarization (BFb, Arg+0° ± 4.0° 16.6° ± 7.2° 26.6° ± 10° 38.5° ± 11° 
Polarization (MFc, Arg+0° ± 3.9° 13.7° ± 4.8° 22.7° ± 6.7° 39.5° ± 7.5° 
a

In the structural analysis, the AdiC structures in the states EO (PDB: 7O82) and EX (PDB: 3L1L) and the BasC and ApcT structures in the states IO (PDB: 6F2G) and IX (PDB: 3GIA) were used. Data are shown as mean ± σ.

b

“BF” indicates the fluorophore rhodamine bifunctionally attached.

c

“MF” indicates the fluorophore ATTO-550 monofunctionally attached.

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