Fit parameters of IQM, CW and CW_IQM before and after ATX-II application used in Figs. 2 and 4
| GV curve . | ||||||
|---|---|---|---|---|---|---|
| Mutants | IQM before ATX | IQM after ATX | CW before ATX | CW after ATX | CW_IQM before ATX | CW_IQM after ATX |
| V50 (mV) | −31.46 ± 0.84 | −35.42 ± 0.83 | −29.45 ± 0.98 | −48.9 ± 0.76 | −35.1 ± 0.85 | −36.66 ± 0.82 |
| Slope (mV) | 5.835 ± 0.762 | 4.781 ± 0.738 | 10.06 ± 0.91 | 5.934 ± 0.69 | 8.062 ± 0.728 | 8.027 ± 0.701 |
| N | 4 | 4 | 5 | 5 | 4 | 4 |
| GV curve . | ||||||
|---|---|---|---|---|---|---|
| Mutants | IQM before ATX | IQM after ATX | CW before ATX | CW after ATX | CW_IQM before ATX | CW_IQM after ATX |
| V50 (mV) | −31.46 ± 0.84 | −35.42 ± 0.83 | −29.45 ± 0.98 | −48.9 ± 0.76 | −35.1 ± 0.85 | −36.66 ± 0.82 |
| Slope (mV) | 5.835 ± 0.762 | 4.781 ± 0.738 | 10.06 ± 0.91 | 5.934 ± 0.69 | 8.062 ± 0.728 | 8.027 ± 0.701 |
| N | 4 | 4 | 5 | 5 | 4 | 4 |