Summary of patches/events for triheteromeric system
| Construct . | Internal soln . | pH . | Interval (s) . | Total events (# of patches) . | Average latency (ms) . | Successes % (global) . | Efficiency (tcrit) . |
|---|---|---|---|---|---|---|---|
| hN1/hN2A (Table 2) | ATP | 7.4 | 10 | 469 (16) | 23 ± 5 | 87 ± 2 (88) | 0.85 ± 0.03 (70.1) |
| rN1/rN2A C1/C2 | no ATP | 7.4 | 10 | 506 (8) | 31 ± 13ns | 87 ± 4ns (89) | nc |
| hN1/hN2B (Table 2) | ATP | 7.4 | 20 | 1,234 (25) | 290 ± 50 | 76 ± 3 (76) | 0.56 ± 0.04 (148) |
| rN1/rN2B C1/C2 | no ATP | 7.4 | 20 | 360 (8) | 190 ± 55ns | 84 ± 4ns (81) | nc |
| rN1 rN2A/rN2B | no ATP | 7.4 | 10 | 509 (7) | 14.5 ± 2 | 89 ± 2 (92) | 0.89 ± 0.02a |
| Construct . | Internal soln . | pH . | Interval (s) . | Total events (# of patches) . | Average latency (ms) . | Successes % (global) . | Efficiency (tcrit) . |
|---|---|---|---|---|---|---|---|
| hN1/hN2A (Table 2) | ATP | 7.4 | 10 | 469 (16) | 23 ± 5 | 87 ± 2 (88) | 0.85 ± 0.03 (70.1) |
| rN1/rN2A C1/C2 | no ATP | 7.4 | 10 | 506 (8) | 31 ± 13ns | 87 ± 4ns (89) | nc |
| hN1/hN2B (Table 2) | ATP | 7.4 | 20 | 1,234 (25) | 290 ± 50 | 76 ± 3 (76) | 0.56 ± 0.04 (148) |
| rN1/rN2B C1/C2 | no ATP | 7.4 | 20 | 360 (8) | 190 ± 55ns | 84 ± 4ns (81) | nc |
| rN1 rN2A/rN2B | no ATP | 7.4 | 10 | 509 (7) | 14.5 ± 2 | 89 ± 2 (92) | 0.89 ± 0.02a |
Values are displayed as in Table 1. Glutamate applications were 1 s in duration. Parameters for the C1/C2 constructs were not significantly different (ns) from their respective wild-type constructs (Student’s t tests): hN2A versus N2A C1/C2 successes, P = 0.94, average latency, P = 0.53; hN2B versus N2B C1/C2 successes, P = 0.13, average delay, P = 0.26. nc, not calculated. h, human; r, rat.
Only a single exponential was needed for fit so success rate = efficiency.