Table 1.

Plasmids and siRNAs

Plasmid nameIdentifierInsertSpecies
LAMP1-mGFP RRID:Addgene_34831 LAMP1 Homo sapiens (human) 
pRK5-LAMP1-FLAG RRID:Addgene_71868 LAMP1 H. sapiens (human) 
LAMP2-BFP Gift from Holzbaur lab (University of Pennsylvania, Philadelphia, PA, USA) (Gallagher and Holzbaur, 2023) LAMP2 H. sapiens (human) 
pMEH371 CD63 HA RRID:Addgene_168220 CD63 H. sapiens (human) 
pLJC5-Tmem192-3xHA RRID:Addgene_102930 TMEM192 H. sapiens (human) 
pcDNA 3.1(+) – hNPC1(WT)-FLAG Custom generated by Genscript, re-cloned from RRID:Addgene_164972 NPC1 H. sapiens (human) 
pRK5-FLAG-C7orf59 RRID:Addgene_42332 LAMTOR4 H. sapiens (human) 
TMEM192 siRNA Santa Cruz Biotech #sc-89327 siRNA to TMEM192 H. sapiens (human) 
Cathepsin D siRNA Santa Cruz Biotech #sc-29239 siRNA to Cathepsin D H. sapiens (human) 
Control siRNA Santa Cruz Biotech #sc-37007 Control siRNA H. sapiens (human) 
Plasmid nameIdentifierInsertSpecies
LAMP1-mGFP RRID:Addgene_34831 LAMP1 Homo sapiens (human) 
pRK5-LAMP1-FLAG RRID:Addgene_71868 LAMP1 H. sapiens (human) 
LAMP2-BFP Gift from Holzbaur lab (University of Pennsylvania, Philadelphia, PA, USA) (Gallagher and Holzbaur, 2023) LAMP2 H. sapiens (human) 
pMEH371 CD63 HA RRID:Addgene_168220 CD63 H. sapiens (human) 
pLJC5-Tmem192-3xHA RRID:Addgene_102930 TMEM192 H. sapiens (human) 
pcDNA 3.1(+) – hNPC1(WT)-FLAG Custom generated by Genscript, re-cloned from RRID:Addgene_164972 NPC1 H. sapiens (human) 
pRK5-FLAG-C7orf59 RRID:Addgene_42332 LAMTOR4 H. sapiens (human) 
TMEM192 siRNA Santa Cruz Biotech #sc-89327 siRNA to TMEM192 H. sapiens (human) 
Cathepsin D siRNA Santa Cruz Biotech #sc-29239 siRNA to Cathepsin D H. sapiens (human) 
Control siRNA Santa Cruz Biotech #sc-37007 Control siRNA H. sapiens (human) 

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