List of genes, homologies, and results of mammalian proteins
| Name (Drosophila) | Name (mammals) | Function | Regulatory hub | Oocyte position defect (>5% defective) | Hanging drop assay defective |
| Canoe | AFADIN | AJ component/actin-binding protein | AJ | Yes | Yes |
| Ataxin-2 | ATXN2 | Aggregation-prone protein, stress granules, and endocytosis | Other | Yes | Yes |
| Sra-1 | CYFIP1/2 | Rac binding/WAVE complex | Actin | Yes | Yes |
| Steamer duck | LIMS1/2 | LIM domain protein and focal adhesions | Adhesion pathways | N/A | No |
| Mlp60A | CSRP1/2 | LIM domain protein and muscle function | Scaffolding domains | No | No |
| Ced-12 | ELMO1/2/3 | RacGEF (DOCK180) | Adhesion pathways | Yes | Yes |
| CG5022 | FRMD3/5 | FERM domain | Scaffolding domains | Yes | No |
| ebi | TBL1/R1 | Wnt signaling, DNA binding, and transcription | Nuclear | Yes | Yes |
| Smrter | NCOR1/2 | DNA binding and transcription | Nuclear | No | No |
| Name (Drosophila) | Name (mammals) | Function | Regulatory hub | Oocyte position defect (>5% defective) | Hanging drop assay defective |
| Canoe | AFADIN | AJ component/actin-binding protein | AJ | Yes | Yes |
| Ataxin-2 | ATXN2 | Aggregation-prone protein, stress granules, and endocytosis | Other | Yes | Yes |
| Sra-1 | CYFIP1/2 | Rac binding/WAVE complex | Actin | Yes | Yes |
| Steamer duck | LIMS1/2 | LIM domain protein and focal adhesions | Adhesion pathways | N/A | No |
| Mlp60A | CSRP1/2 | LIM domain protein and muscle function | Scaffolding domains | No | No |
| Ced-12 | ELMO1/2/3 | RacGEF (DOCK180) | Adhesion pathways | Yes | Yes |
| CG5022 | FRMD3/5 | FERM domain | Scaffolding domains | Yes | No |
| ebi | TBL1/R1 | Wnt signaling, DNA binding, and transcription | Nuclear | Yes | Yes |
| Smrter | NCOR1/2 | DNA binding and transcription | Nuclear | No | No |
N/A, not available.