Km values determined using SSM electrophysiology (pH 7.5)
| . | Gdm+ (mM) ± SEM . | Guanylurea (mM) ± SEM . |
|---|---|---|
| Gdx-Clo | 0.5 ± 0.1 | 0.22 ± 0.06 |
| Gdx-Eco | 1.7 ± 0.5 | 0.85 ± 0.1 |
| Gdx-pPro | 2.9 ± 0.5 | 0.9 ± 0.2 |
| Gdx-pAmi | 15.7 ± 3.3 | 5.2 ± 2.0 |
| . | Gdm+ (mM) ± SEM . | Guanylurea (mM) ± SEM . |
|---|---|---|
| Gdx-Clo | 0.5 ± 0.1 | 0.22 ± 0.06 |
| Gdx-Eco | 1.7 ± 0.5 | 0.85 ± 0.1 |
| Gdx-pPro | 2.9 ± 0.5 | 0.9 ± 0.2 |
| Gdx-pAmi | 15.7 ± 3.3 | 5.2 ± 2.0 |
Values represent mean and SEM from at least three independent sensors prepared from two to three independent protein preps.