Table 4.

Prevalence of auto-Abs against type I IFNs in the general population

Type I IFN auto-Ab (in plasma 1/10)AgeProportion of individuals from the general population with neutralizing auto-Abs (%)
Anti-IFN-α2 (100 pg/ml) Children <18 years 0.2% 
Adults <65 years 0.3% 
Adults ≥65 years 2.6% 
Anti-IFN-ω (100 pg/ml) Children <18 years 2% 
Adults <65 years 0.9% 
Adults ≥65 years 2.2% 
Type I IFN auto-Ab (in plasma 1/10)AgeProportion of individuals from the general population with neutralizing auto-Abs (%)
Anti-IFN-α2 (100 pg/ml) Children <18 years 0.2% 
Adults <65 years 0.3% 
Adults ≥65 years 2.6% 
Anti-IFN-ω (100 pg/ml) Children <18 years 2% 
Adults <65 years 0.9% 
Adults ≥65 years 2.2% 

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