Table 1.

Constructs

ConstructSource
CFP-ARF6 WT, QL, and TN Gift from J. Swanson (#11382, 11386, 11387; Addgene) 
BICD2N-Halo Full-length mouse BICD2 in the pEGFP vector (gift from A. Akhmanova, Utrecht University, Utrecht, Netherlands) was used to generate a truncated construct spanning residues 1–572 fused to the HaloTag and cloned into pcDNA3.1 
Halo-JIP3 (EGFP vector) HaloTag fused to the N-terminus of hJIP3 from cDNA Clone (GE: MGC9053013) fused in pEGFP vector backbone 
Halo-JIP4 (CMV vector) Subcloned from pGEXP1-JIP4 #DU27651, acquired from MRC Protein Phosphorylation and Ubiquitylation Unit reagents and services, University of Dundee, Dundee, UK 
Halo-JIP3 (CMV vector) Halo-JIP3 sequence (from EGFP vector construct) subcloned into (Halo-JIP4) CMV vector 
Halo-JIP4 (EGFP vector) Halo-JIP4 sequence (from CMV vector construct) subcloned into (Halo-JIP3) EGFP vector 
K560-Halo First 560 aa of human KIF5B from pET17: K560 GFP ST (gift from R. Vale, University of California, San Francisco, San Francisco, CA, USA) subcloned into pHTC-HaloTag CMVneo vector (Promega) 
KIF5C-Halo Full-length mouse kinesin-1 heavy chain (KIF5C) in pRK5 myc plasmid (gift from J. Kittler, University of Surrey, Guildford, UK) with HaloTag fused to C-terminus 
GFP-KLC2 Full-length WT mouse KLC2 in CB6 driven expression vector 
LAMP1-mNEON Gift from D. Gadella (plasmid #98882; Addgene) 
mCh-EGFP-LC3B Gift from T. Johansen, University of Tromsø, Tromsø, Norway 
mSc-LC3B Subcloned from #21073 and #85054; Addgene 
HA-LIS1 Gift from D. Smith, University of South Carolina, Columbia, SC, USA 
EGFP-RAB10 Gift from M. Scidmore (plasmid #49472; Addgene) 
ConstructSource
CFP-ARF6 WT, QL, and TN Gift from J. Swanson (#11382, 11386, 11387; Addgene) 
BICD2N-Halo Full-length mouse BICD2 in the pEGFP vector (gift from A. Akhmanova, Utrecht University, Utrecht, Netherlands) was used to generate a truncated construct spanning residues 1–572 fused to the HaloTag and cloned into pcDNA3.1 
Halo-JIP3 (EGFP vector) HaloTag fused to the N-terminus of hJIP3 from cDNA Clone (GE: MGC9053013) fused in pEGFP vector backbone 
Halo-JIP4 (CMV vector) Subcloned from pGEXP1-JIP4 #DU27651, acquired from MRC Protein Phosphorylation and Ubiquitylation Unit reagents and services, University of Dundee, Dundee, UK 
Halo-JIP3 (CMV vector) Halo-JIP3 sequence (from EGFP vector construct) subcloned into (Halo-JIP4) CMV vector 
Halo-JIP4 (EGFP vector) Halo-JIP4 sequence (from CMV vector construct) subcloned into (Halo-JIP3) EGFP vector 
K560-Halo First 560 aa of human KIF5B from pET17: K560 GFP ST (gift from R. Vale, University of California, San Francisco, San Francisco, CA, USA) subcloned into pHTC-HaloTag CMVneo vector (Promega) 
KIF5C-Halo Full-length mouse kinesin-1 heavy chain (KIF5C) in pRK5 myc plasmid (gift from J. Kittler, University of Surrey, Guildford, UK) with HaloTag fused to C-terminus 
GFP-KLC2 Full-length WT mouse KLC2 in CB6 driven expression vector 
LAMP1-mNEON Gift from D. Gadella (plasmid #98882; Addgene) 
mCh-EGFP-LC3B Gift from T. Johansen, University of Tromsø, Tromsø, Norway 
mSc-LC3B Subcloned from #21073 and #85054; Addgene 
HA-LIS1 Gift from D. Smith, University of South Carolina, Columbia, SC, USA 
EGFP-RAB10 Gift from M. Scidmore (plasmid #49472; Addgene) 

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