List of proteins significantly absent and reduced at least fourfold from FAP256A/B-KO compared with CU428 along with their human homologs, known localization, percent coverage, emPAI score, and number of peptides
| Absent or decreased at least fourfold in FAP256A/B-KO cells . | Uniprot ID . | Name . | Amino acids . | Human homolog? . | % identity . | Known localization? . | Percent coverage (highest of repeats) . | emPAI score . | Number of peptides (average of WT) . |
|---|---|---|---|---|---|---|---|---|---|
| Absent | I7MLF6 | EF hand protein | 1766 | CCDC81 | 23.74 | Centrosome | 7.53 | 0.169 | 8.7 |
| Absent | Q22US8 | Uncharacterized protein | 798 | 2.88 | 0.054 | 1.3 | |||
| Absent | I7MKU9 | Uncharacterized protein | 1730 | 2.08 | 0.046 | 2.3 | |||
| Absent | Q24IJ6 | Tetratricopeptide repeat protein | 519 | TPR repeat protein 28 | 24.07 | Microtubule organizing center | 8.09 | 0.225 | 3 |
| Absent | Q23FN3 | FAP256 | 872 | CEP104 | 29.05 | Cilia and centriole | 20.3 | 0.392 | 8.3 |
| Absent | I7LVP2 | Divergent AAA domain protein | 273 | SLFNL1 | 30.77 | Sperm cells | 16.5 | 0.438 | 3.3 |
| Absent | I7MH51 | Uncharacterized protein | 474 | 10.1 | 0.123 | 1.7 | |||
| Absent | I7LTB1 | FAP256B | 1017 | CEP104 | 25.98 | Cilia and centriole | 2.75 | 0.015 | 0.7 |
| Decreased at least fourfold | Q22Y55 | Phosphatase 2A | 579 | PP2A | 34.15 | Ubiquitous | 50.4 | 1.419 | 16.3 |
| Decreased at least fourfold | Q229R5 | Ser/Thr phosphatase | 313 | PP2A | 70.1 | 17.3 | 0.497 | 3.7 | |
| Decreased at least fourfold | I7LX00 | Group 1 truncated haemoglobin | 121 | 56.2 | 2.929 | 4 | |||
| Decreased at least fourfold | I7LVY1 | Kinesin motor catalytic domain protein | 1066 | Kif16B | 29.75 | Early endosomes | 14.9 | 0.284 | 7.7 |
| Decreased at least fourfold | Q22D06 | WD domain, G-beta repeat protein | 2585 | Dynein assembly factor with WDR repeat domains | 34.2 | Cilia | 8.55 | 0.171 | 13.7 |
| Decreased at least fourfold | Q24CF9 | WD domain, G-beta repeat protein | 2207 | Dynein assembly factor with WDR repeat domains | 25.82 | Cilia | 27.5 | 0.79 | 38 |
| Decreased at least fourfold | I7M9E4 | ATP:guanido phosphotransferase, carboxy-terminal domain protein | 370 | Creatine kinase | 41.87 | Ubiquitous | 41.4 | 3.474 | 12.3 |
| Decreased at least fourfold | Q23DC5 | Thioredoxin glutathione reductase | 491 | Thioredoxin reductase | 55.7 | Ubiquitous | 7.74 | 0.177 | 2.3 |
| Decreased at least fourfold | I7LU65 | C2 domain protein | 841 | Coiled-coil domain-containing protein 33 | 26.24 | Peroxisome | 9.99 | 0.278 | 5.7 |
| Decreased at least fourfold | I7MMW4 | STOP Protein | 592 | 19.8 | 0.441 | 6.7 | |||
| Decreased at least fourfold | Q22F01 | Phospholipid scramblase | 277 | 14.8 | 0.718 | 3.3 |
| Absent or decreased at least fourfold in FAP256A/B-KO cells . | Uniprot ID . | Name . | Amino acids . | Human homolog? . | % identity . | Known localization? . | Percent coverage (highest of repeats) . | emPAI score . | Number of peptides (average of WT) . |
|---|---|---|---|---|---|---|---|---|---|
| Absent | I7MLF6 | EF hand protein | 1766 | CCDC81 | 23.74 | Centrosome | 7.53 | 0.169 | 8.7 |
| Absent | Q22US8 | Uncharacterized protein | 798 | 2.88 | 0.054 | 1.3 | |||
| Absent | I7MKU9 | Uncharacterized protein | 1730 | 2.08 | 0.046 | 2.3 | |||
| Absent | Q24IJ6 | Tetratricopeptide repeat protein | 519 | TPR repeat protein 28 | 24.07 | Microtubule organizing center | 8.09 | 0.225 | 3 |
| Absent | Q23FN3 | FAP256 | 872 | CEP104 | 29.05 | Cilia and centriole | 20.3 | 0.392 | 8.3 |
| Absent | I7LVP2 | Divergent AAA domain protein | 273 | SLFNL1 | 30.77 | Sperm cells | 16.5 | 0.438 | 3.3 |
| Absent | I7MH51 | Uncharacterized protein | 474 | 10.1 | 0.123 | 1.7 | |||
| Absent | I7LTB1 | FAP256B | 1017 | CEP104 | 25.98 | Cilia and centriole | 2.75 | 0.015 | 0.7 |
| Decreased at least fourfold | Q22Y55 | Phosphatase 2A | 579 | PP2A | 34.15 | Ubiquitous | 50.4 | 1.419 | 16.3 |
| Decreased at least fourfold | Q229R5 | Ser/Thr phosphatase | 313 | PP2A | 70.1 | 17.3 | 0.497 | 3.7 | |
| Decreased at least fourfold | I7LX00 | Group 1 truncated haemoglobin | 121 | 56.2 | 2.929 | 4 | |||
| Decreased at least fourfold | I7LVY1 | Kinesin motor catalytic domain protein | 1066 | Kif16B | 29.75 | Early endosomes | 14.9 | 0.284 | 7.7 |
| Decreased at least fourfold | Q22D06 | WD domain, G-beta repeat protein | 2585 | Dynein assembly factor with WDR repeat domains | 34.2 | Cilia | 8.55 | 0.171 | 13.7 |
| Decreased at least fourfold | Q24CF9 | WD domain, G-beta repeat protein | 2207 | Dynein assembly factor with WDR repeat domains | 25.82 | Cilia | 27.5 | 0.79 | 38 |
| Decreased at least fourfold | I7M9E4 | ATP:guanido phosphotransferase, carboxy-terminal domain protein | 370 | Creatine kinase | 41.87 | Ubiquitous | 41.4 | 3.474 | 12.3 |
| Decreased at least fourfold | Q23DC5 | Thioredoxin glutathione reductase | 491 | Thioredoxin reductase | 55.7 | Ubiquitous | 7.74 | 0.177 | 2.3 |
| Decreased at least fourfold | I7LU65 | C2 domain protein | 841 | Coiled-coil domain-containing protein 33 | 26.24 | Peroxisome | 9.99 | 0.278 | 5.7 |
| Decreased at least fourfold | I7MMW4 | STOP Protein | 592 | 19.8 | 0.441 | 6.7 | |||
| Decreased at least fourfold | Q22F01 | Phospholipid scramblase | 277 | 14.8 | 0.718 | 3.3 |