Kinetic parameters reflecting probabilities of crossbridges to enter and leave force-generating states of replated hESC-CMs
| Cross-bridge related parameters | Replated hESC-CMs | Non-replated | |
|---|---|---|---|
| 2 d | 9 d | 35 d hESC-CMs | |
| fapp | 1.32 ± 0.75** | 0.56 ± 0.16ns | 0.47 ± 0.11 |
| gapp | 0.64 ± 0.11** | 0.33 ± 0.13ns | 0.26 ± 0.06 |
| Cross-bridge related parameters | Replated hESC-CMs | Non-replated | |
|---|---|---|---|
| 2 d | 9 d | 35 d hESC-CMs | |
| 1.32 ± 0.75** | 0.56 ± 0.16ns | 0.47 ± 0.11 | |
| 0.64 ± 0.11** | 0.33 ± 0.13ns | 0.26 ± 0.06 | |
Kinetic parameters reflecting probabilities of crossbridges to enter (fapp) and leave (gapp) force-generating states of replated cells on indicated days, and of non-replated 35 d hESC-CMs with predominant exclusive β-MyHC expression (data imported from Iorga et al. [2018]). Data were calculated as indicated in Fig. 2, C and D. Mean ± SD; **, P < 0.01; ns, not significant, P > 0.05).