Table 1. Urea, thiourea, and diffusional... | Rockefeller University Press

Table 1.

Urea, thiourea, and diffusional water permeability in human RBCs from three donors

Donor	P_u	SD	n	P_tu	SD	n	P_d	SD	n	P_tu/P_u	P_d/P_u
	cm/s × 10⁴			cm/s × 10⁷			cm/s × 10³			× 10³
JBR	2.67^{^a}			2.90	± 0.28	7	2.4^{^b}			1.1	9.0
D50	4.36	± 0.16	2	4.38	± 0.59	11	2.38	± 0.09	3	1.0	5.5
JSK	5.88^{^a}			4.78	± 0.21	3	2.45	± 0.16	6	0.8	4.2

Donor	P_u	SD	n	P_tu	SD	n	P_d	SD	n	P_tu/P_u	P_d/P_u
	cm/s × 10⁴			cm/s × 10⁷			cm/s × 10³			× 10³
JBR	2.67^a			2.90	± 0.28	7	2.4^b			1.1	9.0
D50	4.36	± 0.16	2	4.38	± 0.59	11	2.38	± 0.09	3	1.0	5.5
JSK	5.88^a			4.78	± 0.21	3	2.45	± 0.16	6	0.8	4.2

From Brahm (1983b).

From Brahm (1982). P_u and P_d values are determined at 25°C, pH 7.2, 1 mM urea. P_tu values are determined at 0°C, pH 7.2 to minimize the fraction of thiourea that permeates the lipid phase of the membrane.

[ViewLarge]

Sharing Unavailable