Table 1.

Urea, thiourea, and diffusional water permeability in human RBCs from three donors

DonorPuSDnPtuSDnPdSDnPtu/PuPd/Pu
 cm/s × 104  cm/s × 107  cm/s × 103  × 103  
JBR 2.67a   2.90 ± 0.28 2.4b   1.1 9.0 
D50 4.36 ± 0.16 4.38 ± 0.59 11 2.38 ± 0.09 1.0 5.5 
JSK 5.88a   4.78 ± 0.21 2.45 ± 0.16 0.8 4.2 
DonorPuSDnPtuSDnPdSDnPtu/PuPd/Pu
 cm/s × 104  cm/s × 107  cm/s × 103  × 103  
JBR 2.67a   2.90 ± 0.28 2.4b   1.1 9.0 
D50 4.36 ± 0.16 4.38 ± 0.59 11 2.38 ± 0.09 1.0 5.5 
JSK 5.88a   4.78 ± 0.21 2.45 ± 0.16 0.8 4.2 
a

From Brahm (1983b).

b

From Brahm (1982). Pu and Pd values are determined at 25°C, pH 7.2, 1 mM urea. Ptu values are determined at 0°C, pH 7.2 to minimize the fraction of thiourea that permeates the lipid phase of the membrane.

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