Table II.

Whole cell PAGFP equilibration parameters

Cell t1/2 equilibration DCC, Flux method DCC, 1-D rod model DOS, (axial) 
 min µm2 s−1 µm2 s−1 µm2 s−1 
4.5 3.3 0.096 
6.7 2.0 1.3 0.117 
9.2 4.0 2.5 0.075 
5.3 1.4 1.3 0.117 
nd nd 3.4 0.062 
3.7 nd 0.074 
11.5 1.0 1.4 0.033 
9.9 nd 1.6 0.083 
3.45 nd 2.0 0.050 
mean ± SEM 7.0 ± 1.0 2.8 ± 0.5ab 2.1 ± 0.3ab 0.079 ± 0.009b 
Cell t1/2 equilibration DCC, Flux method DCC, 1-D rod model DOS, (axial) 
 min µm2 s−1 µm2 s−1 µm2 s−1 
4.5 3.3 0.096 
6.7 2.0 1.3 0.117 
9.2 4.0 2.5 0.075 
5.3 1.4 1.3 0.117 
nd nd 3.4 0.062 
3.7 nd 0.074 
11.5 1.0 1.4 0.033 
9.9 nd 1.6 0.083 
3.45 nd 2.0 0.050 
mean ± SEM 7.0 ± 1.0 2.8 ± 0.5ab 2.1 ± 0.3ab 0.079 ± 0.009b 
a

Difference between DCC obtained by flux method and that obtained from the 1-D rod model was not significant (P = 0.21).

b

Differences between DCC measured by either method and DOS were significant at the P = 0.01 level.

or Create an Account

Close Modal
Close Modal