Midpoints and slope factors of the activation curves of CaV1.2 IIS6 mutants
| Mutant | Half-activation | Slope |
| mV | mV | |
| Wild-typea | −9.9 ± 1.1 | 6.3 ± 0.7 |
| A780Pa | −37.1 ± 0.7 | 5.7 ± 0.8 |
| A780G | −19.3 ± 0.8 | 6.3 ± 0.6 |
| I781Pa | −47.2 ± 1.1 | 6.3 ± 0.6 |
| I781G | −40.2 ± 0.8 | 7.5 ± 0.7 |
| I781Ta | −37.7 ± 1.2 | 7.2 ± 1.0 |
| A782Pa | −35.7 ± 1.4 | 9.8 ± 0.3 |
| A782G | −22.2 ± 0.4 | 7.8 ± 0.4 |
| V783G | No current | No current |
| D784G | −15.6 ± 1.1 | 6.3 ± 0.6 |
| Mutant | Half-activation | Slope |
| Wild-type | −9.9 ± 1.1 | 6.3 ± 0.7 |
| A780P | −37.1 ± 0.7 | 5.7 ± 0.8 |
| A780G | −19.3 ± 0.8 | 6.3 ± 0.6 |
| I781P | −47.2 ± 1.1 | 6.3 ± 0.6 |
| I781G | −40.2 ± 0.8 | 7.5 ± 0.7 |
| I781T | −37.7 ± 1.2 | 7.2 ± 1.0 |
| A782P | −35.7 ± 1.4 | 9.8 ± 0.3 |
| A782G | −22.2 ± 0.4 | 7.8 ± 0.4 |
| V783G | No current | No current |
| D784G | −15.6 ± 1.1 | 6.3 ± 0.6 |
Data from Hohaus et al. (2005).
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