Table I. Spike and SAF parameters:... | Rockefeller University Press

Table I.

Spike and SAF parameters: control versus 100 µM ryanodine

Parameter	Control mean ± SEM	100 µM ryanodine mean ± SEM	p-value
Spikes
Amplitude (pA)	9.20 ± 2.3	15.90 ± 1.6	*0.026
Rise time^a (ms)	6.78 ± 0.65	10.83 ± 0.95	*0.002
Half-width (ms)	11.79 ± 0.89	15.23 ± 1.5	0.068
τ^b (ms)	11.45 ± 0.87	14.23 ± 1.38	0.099
Duration (ms)	62.99 ± 4.86	84.49 ± 7.56	*0.027
SAFs
Amplitude (pA)	1.09 ± 0.03	1.84 ± 0.06	*0.000
Duration (ms)	32.68 ± 3.6	33.55 ± 4.3	0.877

Parameter	Control mean ± SEM	100 µM ryanodine mean ± SEM	p-value
Spikes
Amplitude (pA)	9.20 ± 2.3	15.90 ± 1.6	*0.026
Rise time^a (ms)	6.78 ± 0.65	10.83 ± 0.95	*0.002
Half-width (ms)	11.79 ± 0.89	15.23 ± 1.5	0.068
τ^b (ms)	11.45 ± 0.87	14.23 ± 1.38	0.099
Duration (ms)	62.99 ± 4.86	84.49 ± 7.56	*0.027
SAFs
Amplitude (pA)	1.09 ± 0.03	1.84 ± 0.06	*0.000
Duration (ms)	32.68 ± 3.6	33.55 ± 4.3	0.877

p-values are from two sample Student's t tests.

Rise time is 10–90%.

τ is 67% decay.