TABLE IV

Parameters from Boltzmann Fits to G-V Relations

Channel
V1/2
ΔV1/2
z
Δz
n
Ctrl −30.3 ± 0.9 n/a 2.4 ± 0.2 n/a 3–11 
S654C −33.3 ± 0.6a −2.0 2.3 ± 0.12 −0.11 7 
I655C −30.9 ± 0.9 −0.6 1.82 ± 0.11a −0.59 11–12 
F656C −28.0 ± 0.6 +2.3 1.99 ± 0.09 −0.41 5 
G657Cb −67.6 ± 0.5c −37.3 2.70 ± 0.24 −0.30 5 
N658C −3.38 ± 0.9c +26.9 1.58 ± 0.09a −0.83 3 
V659C −23.8 ± 1.9a +6.5 1.11 ± 0.10a −1.30 3 
S660C −27.6 ± 1.0 +2.7 1.99 ± 0.15 −0.41 4 
A661C −8.6 ± 0.5c +21.7 1.97 ± 0.07a −0.43 7 
I662C −44.5 ± 1.5c −14.2 1.70 ± 0.15a −0.71 11 
I663C −7.7 ± 0.6c +22.6 1.94 ± 0.08a −0.46 9 
Q664C −22.8 ± 0.5a +7.5 2.38 ± 0.11 −0.02 3–6 
R665Cb −30.5 ± 0.4 −0.20 2.9 ± 0.16a +0.07 4 
L666C −32.2 ± 0.8 −1.9 2.46 ± 0.16 +0.05 3–11 
Y667C −36.9 ± 0.4a −6.6 2.47 ± 0.08 +0.06 3 
S668Cb −44.4 ± 1.7c −14.1 2.93 ± 0.58 +0.53 15 

Values are derived from Boltzmann fits to steady-state activation data (see Materials and methods). Values are ± SEM.

a

P < 0.05.

b

Fit with an empirical double Boltzmann function (see Materials and methods). Values corresponding to the first function are reported.

c

P < 0.001.

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