TABLE II

Parameters from Fits to V659 Mutant Recordings

Channel
Average Deactivation τ at −100 mV
V1/2
ΔV1/2
z
Δz
n
Ctrl 123.9 ± 6.1 −30.3 ± 0.9 n/a 2.4 ± 0.2 n/a 3–11 
V659A 850.9 ± 83.3a −30.8 ± 19.4 +0.5 0.38 ± 0.08a −2.03 4 
V659C 765.6 ± 53.4a −23.8 ± 1.9b +6.5 1.11 ± 0.1b −1.30 3 
V659F 891.1 ± 62.5a −14.7 ± 3.2b +15.4 1.13 ± 0.17b −1.27 3 
V659Ic 489.8 ± 81.7a −36.6 ± 0.3 −6.3 2.65 ± 0.07b +0.25 3 
V659T 1,110.6 ± 235.1a −2.3 ± 4.7a +28.0 0.85 ± 0.14b −1.56 3 

Values are ± SEM.

a

P < 0.001.

b

P < 0.05.

c

Fit with an empirical double Boltzmann function. Values corresponding to the first function are reported.

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