TABLE II Summary of V 1/2 Changes... | Rockefeller University Press

TABLE II

Summary of V_1/2 Changes Associated with Various Kv1.2 and Shaker Mutations

	n	V_1/2	ΔV_1/2 from WT
		mV	mV
Shaker-WT	10	−17.2 ± 0.6
Shaker-G420D	10	−23.7 ± 0.8	−6.5
Shaker-S421E	10	−17.8 ± 0.7	−0.6
Shaker-G420D-S421E	10	−25.7 ± 0.9	−8.5
Kv1.2-WT	10	−14.8 ± 0.5
Kv1.2-D352G	10	−9.9 ± 0.6	+4.9
Kv1.2-E353S	10	−13.2 ± 0.7	+1.6
Kv1.2-D352G-E353S	10	−5.4 ± 0.6	+9.4

	n	V_1/2	ΔV_1/2 from WT
		mV	mV
Shaker-WT	10	−17.2 ± 0.6
Shaker-G420D	10	−23.7 ± 0.8	−6.5
Shaker-S421E	10	−17.8 ± 0.7	−0.6
Shaker-G420D-S421E	10	−25.7 ± 0.9	−8.5
Kv1.2-WT	10	−14.8 ± 0.5
Kv1.2-D352G	10	−9.9 ± 0.6	+4.9
Kv1.2-E353S	10	−13.2 ± 0.7	+1.6
Kv1.2-D352G-E353S	10	−5.4 ± 0.6	+9.4