Summary Data of Effects of Recombinant N-terminal Proteins on Tension–pCa Relationships
| Protein (n) . | [ ] (μM) . | pCa50 (Control) . | pCa50 (After protein) . | ΔpCa50 . | Hill coefficient (nH) (Control) . | Hill coefficient (nH) (After protein) . |
|---|---|---|---|---|---|---|
| C0C2 (6) | 5 | 5.32 ± 0.02 | 5.73 ± 0.05a | 0.42 ± 0.04 | 5.43 ± 0.32 | 2.19 ± 0.14a |
| C1C2 (4) | 5 | 5.30 ± 0.02 | 5.54 ± 0.03a | 0.25 ± 0.05 | 6.45 ± 0.86 | 2.65 ± 0.25a |
| C0C1m (4) | 5 | 5.32 ± 0.01 | 5.59 ± 0.05a | 0.27 ± 0.05 | 7.66 ± 0.72 | 2.71 ± 0.34a |
| C1m (6) | 5 | 5.34 ± 0.02 | 5.46 ± 0.04a | 0.12 ± 0.04 | 6.83 ± 0.89 | 3.72 ± 0.34a |
| C1C2 (5) | 10 | 5.29 ± 0.02 | 5.58 ± 0.05a | 0.30 ± 0.05 | 5.02 ± 0.33 | 2.11 ± 0.14a |
| mC2 (4) | 10 | 5.30 ± 0.01 | 5.32 ± 0.03 | 0.02 ± 0.03 | 6.63 ± 0.44 | 5.90 ± 0.67 |
| C0C1 (3) | 10 | 5.34 ± 0.01 | 5.32 ± 0.01 | −0.02 ± 0.01 | 6.61 ± 0.70 | 7.50 ± 0.83 |
| C2C4 (4) | 20 | 5.32 ± 0.01 | 5.32 ± 0.01 | 0.00 ± 0.01 | 6.73 ± 0.21 | 6.15 ± 0.71 |
| C1C2(-m) (3) | 20 | 5.33 ± 0.02 | 5.34 ± 0.01 | 0.01 ± 0.01 | 9.62 ± 2.078 | 8.67 ± 2.04 |
| C3mC4 (3) | 20 | 5.30 ± 0.02 | 5.29 ± 0.02 | −0.01 ± 0.01 | 4.96 ± 0.62 | 5.56 ± 0.42 |
| Protein (n) . | [ ] (μM) . | pCa50 (Control) . | pCa50 (After protein) . | ΔpCa50 . | Hill coefficient (nH) (Control) . | Hill coefficient (nH) (After protein) . |
|---|---|---|---|---|---|---|
| C0C2 (6) | 5 | 5.32 ± 0.02 | 5.73 ± 0.05a | 0.42 ± 0.04 | 5.43 ± 0.32 | 2.19 ± 0.14a |
| C1C2 (4) | 5 | 5.30 ± 0.02 | 5.54 ± 0.03a | 0.25 ± 0.05 | 6.45 ± 0.86 | 2.65 ± 0.25a |
| C0C1m (4) | 5 | 5.32 ± 0.01 | 5.59 ± 0.05a | 0.27 ± 0.05 | 7.66 ± 0.72 | 2.71 ± 0.34a |
| C1m (6) | 5 | 5.34 ± 0.02 | 5.46 ± 0.04a | 0.12 ± 0.04 | 6.83 ± 0.89 | 3.72 ± 0.34a |
| C1C2 (5) | 10 | 5.29 ± 0.02 | 5.58 ± 0.05a | 0.30 ± 0.05 | 5.02 ± 0.33 | 2.11 ± 0.14a |
| mC2 (4) | 10 | 5.30 ± 0.01 | 5.32 ± 0.03 | 0.02 ± 0.03 | 6.63 ± 0.44 | 5.90 ± 0.67 |
| C0C1 (3) | 10 | 5.34 ± 0.01 | 5.32 ± 0.01 | −0.02 ± 0.01 | 6.61 ± 0.70 | 7.50 ± 0.83 |
| C2C4 (4) | 20 | 5.32 ± 0.01 | 5.32 ± 0.01 | 0.00 ± 0.01 | 6.73 ± 0.21 | 6.15 ± 0.71 |
| C1C2(-m) (3) | 20 | 5.33 ± 0.02 | 5.34 ± 0.01 | 0.01 ± 0.01 | 9.62 ± 2.078 | 8.67 ± 2.04 |
| C3mC4 (3) | 20 | 5.30 ± 0.02 | 5.29 ± 0.02 | −0.01 ± 0.01 | 4.96 ± 0.62 | 5.56 ± 0.42 |
Significance, P < 0.05 versus control.