Single-Channel Properties of MEC-4d/10d Channels and Effects of Auxiliary Subunits
. | γ1 (pS) . | Po1 . | γ2 (pS) . | Po2 . | 〈γ〉 (pS) . | Po . |
|---|---|---|---|---|---|---|
| MEC-4d/10d | 19.3 ± 4.3 (11) | 0.38 ± 0.27 (11) | 29.3 ± 4.9 (11) | 0.42 ± 0.33 (11) | 17.0 ± 6.8 (11) | 0.72 ± 0.20 (11) |
| +MEC-2 | ND | ND | 38.3 ± 1.6 (8)a | NA | 31.8 ± 7.2 (8)a | 0.79 ± 0.26 (8) |
| +MEC-6 | ND | ND | 30.2 ± 5.7 (6) | NA | 24.9 ± 6.1 (6)a | 0.72 ± 0.42 (6) |
| +MEC-2 +MEC-6 | 23.1 ± 2.5 (5) | 0.46 ± 0.27 (5) | 36.3 ± 1.6 (5)a | 0.42 ± 0.29 (5) | 25.6 ± 5.3 (5)a | 0.89 ± 0.04 (5) |
. | γ1 (pS) . | Po1 . | γ2 (pS) . | Po2 . | 〈γ〉 (pS) . | Po . |
|---|---|---|---|---|---|---|
| MEC-4d/10d | 19.3 ± 4.3 (11) | 0.38 ± 0.27 (11) | 29.3 ± 4.9 (11) | 0.42 ± 0.33 (11) | 17.0 ± 6.8 (11) | 0.72 ± 0.20 (11) |
| +MEC-2 | ND | ND | 38.3 ± 1.6 (8)a | NA | 31.8 ± 7.2 (8)a | 0.79 ± 0.26 (8) |
| +MEC-6 | ND | ND | 30.2 ± 5.7 (6) | NA | 24.9 ± 6.1 (6)a | 0.72 ± 0.42 (6) |
| +MEC-2 +MEC-6 | 23.1 ± 2.5 (5) | 0.46 ± 0.27 (5) | 36.3 ± 1.6 (5)a | 0.42 ± 0.29 (5) | 25.6 ± 5.3 (5)a | 0.89 ± 0.04 (5) |
Po ANOVA: F(3,26) = 2.06, P = 0.13. γ ANOVA: F(3,24) = 9.3, P < 0.0005.
P < 0.01 by one-way t test compared to MEC-4d/10d.