Parameter Values Used in All Calculations
| Parameter | Symbol | Value | Reference |
|---|---|---|---|
| Water dielectric | εw | 80 | Floris et al., 1991 |
| Protein dielectric | εp | 2 | Gallicchio et al., 2000 |
| Membrane core dielectric | εhc | 2 | Long et al., 2007 |
| Lipid head group dielectric | εhg | 80 | Long et al., 2007 |
| Equilibrium membrane width | L0 | 42 Å | Nielsen and Andersen, 2000 |
| Head group width | Lhg | 8 Å | Lipowsky and Sackman, 1995 |
| Ion screening concentration | Ic | 100 mM | Shrake and Rupley, 1973 |
| Bulk interfacial surface tension | α | 3 × 10−13 N/Å | Jacobs and White, 1989 |
| Area compression-expansion modulus | Ka | 1.425 × 10−11 N/Å | Jacobs and White, 1989 |
| Bending or splay-distortion modulus | Kc | 2.85 × 10−10 NÅ | Jacobs and White, 1989 |
| α/Kc | γ | 1.05 × 10−3 Å−2 | Jacobs and White, 1989 |
| 2 Ka/(L02·Kc) | β | 5.66 × 10−5 Å−4 | Jacobs and White, 1989 |
| SASA prefactor for nonpolar energy | a | 0.028 kcal/mol·Å2 | Gallicchio et al., 2000 |
| Constant term for nonpolar energy | b | −1.7 kcal/mol | Gallicchio et al., 2000 |
| Parameter | Symbol | Value | Reference |
|---|---|---|---|
| Water dielectric | εw | 80 | |
| Protein dielectric | εp | 2 | |
| Membrane core dielectric | εhc | 2 | |
| Lipid head group dielectric | εhg | 80 | |
| Equilibrium membrane width | L0 | 42 Å | |
| Head group width | Lhg | 8 Å | |
| Ion screening concentration | Ic | 100 mM | |
| Bulk interfacial surface tension | α | 3 × 10−13 N/Å | |
| Area compression-expansion modulus | Ka | 1.425 × 10−11 N/Å | |
| Bending or splay-distortion modulus | Kc | 2.85 × 10−10 NÅ | |
| α/Kc | γ | 1.05 × 10−3 Å−2 | |
| 2 Ka/(L02·Kc) | β | 5.66 × 10−5 Å−4 | |
| SASA prefactor for nonpolar energy | a | 0.028 kcal/mol·Å2 | |
| Constant term for nonpolar energy | b | −1.7 kcal/mol |
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