Relative Permeability to cAMP and LY and Estimated Pore Diameter of Cx26, Cx40, and Cx43 Channels
. | Cx26 . | Cx40 . | Cx43 . |
|---|---|---|---|
| cAMP/K+ | 0.027 | 0.018 | 0.180 |
| LY/K+ | 0.0043 | 0.0026 | 0.029 |
| cAMP/LY | 6.3 | 6.9 | 6.2 |
| Estimated pore diameter (nm) | |||
| from cAMP (0.52 nm, minor diameter) | 0.69 | 0.65 | 1.12 |
| from LY (0.95 nm, minor diameter) | 1.1 | 1.08 | 1.25 |
. | Cx26 . | Cx40 . | Cx43 . |
|---|---|---|---|
| cAMP/K+ | 0.027 | 0.018 | 0.180 |
| LY/K+ | 0.0043 | 0.0026 | 0.029 |
| cAMP/LY | 6.3 | 6.9 | 6.2 |
| Estimated pore diameter (nm) | |||
| from cAMP (0.52 nm, minor diameter) | 0.69 | 0.65 | 1.12 |
| from LY (0.95 nm, minor diameter) | 1.1 | 1.08 | 1.25 |