TABLE III

Burst Analysis for α4β2δ and α1β2γ2S GABAARs

τC1 (ms) [AC1]
τC2 (ms) [AC2]
τC3 (ms) [AC3]
τO1 (ms) [AO1]
τO2 (ms) [AO2]
τO3 (ms) [AO3]
α4β2δ 10 mM THIP (n = 5) 1.04 ± 0.47 [0.31 ± 0.10] 14.9 ± 4.8 [0.69 ± 0.10] – 1.76 ± 0.57 [0.49 ± 0.10] 7.70 ± 2.03 [0.51 ± 0.11] – 
 10 mM THIP (n = 3) 2.98 ± 0.31 [0.74 ± 0.06]
 		18.3 ± 2.3 [0.26 ± 0.06]
 		–
 		2.16 ± 0.70 [0.34 ± 0.11]
 		6.76 ± 1.29 [0.66 ± 0.11]
 		–
 
 10 mM GABA M–Mode (n = 10)
 		     
α1β2γ2S  0.26 ± 0.02 [0.48 ± 0.03]
 		1.12 ± 0.14 [0.31 ± 0.03]
 		3.87 ± 0.41 [0.21 ± 0.03]
 		0.49 ± 0.02 [0.26 ± 0.03]
 		2.58 ± 0.09 [0.49 ± 0.04]
 		5.17 ± 0.38 [0.25 ± 0.04]
 
  H–Mode (n = 5)
 		     
  0.34 ± 0.04 [0.58 ± 0.05] 1.94 ± 0.22 [0.42 ± 0.03] – 0.59 ± 0.11 [0.18 ± 0.02] 4.22 ± 0.73 [0.41 ± 0.03] 13.2 ± 2.6 [0.41 ± 0.05]  
τC1 (ms) [AC1]
τC2 (ms) [AC2]
τC3 (ms) [AC3]
τO1 (ms) [AO1]
τO2 (ms) [AO2]
τO3 (ms) [AO3]
α4β2δ 10 mM THIP (n = 5) 1.04 ± 0.47 [0.31 ± 0.10] 14.9 ± 4.8 [0.69 ± 0.10] – 1.76 ± 0.57 [0.49 ± 0.10] 7.70 ± 2.03 [0.51 ± 0.11] – 
 10 mM THIP (n = 3) 2.98 ± 0.31 [0.74 ± 0.06]
 		18.3 ± 2.3 [0.26 ± 0.06]
 		–
 		2.16 ± 0.70 [0.34 ± 0.11]
 		6.76 ± 1.29 [0.66 ± 0.11]
 		–
 
 10 mM GABA M–Mode (n = 10)
 		     
α1β2γ2S  0.26 ± 0.02 [0.48 ± 0.03]
 		1.12 ± 0.14 [0.31 ± 0.03]
 		3.87 ± 0.41 [0.21 ± 0.03]
 		0.49 ± 0.02 [0.26 ± 0.03]
 		2.58 ± 0.09 [0.49 ± 0.04]
 		5.17 ± 0.38 [0.25 ± 0.04]
 
  H–Mode (n = 5)
 		     
  0.34 ± 0.04 [0.58 ± 0.05] 1.94 ± 0.22 [0.42 ± 0.03] – 0.59 ± 0.11 [0.18 ± 0.02] 4.22 ± 0.73 [0.41 ± 0.03] 13.2 ± 2.6 [0.41 ± 0.05]  
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