TABLE I Permeability Ratios of Na... | Rockefeller University Press

TABLE I

Permeability Ratios of Na⁺ Channel Selectivity Filter Mutants

Mutant		P_K/P_Na
	Favre^{^a}	Schlief^{^b}	Sun^{^c}
DEKA	0.03 ± 0.01	0.10 ± 0.03	0.08 ± 0.01
AEKA	0.03 ± 0.03	–	–
DAKA	0.09 ± 0.03	–	–
DEKD	–	0.23 ± 0.05	–
DKEA	–	0.37 ± 0.03	–
DEAA	1.1 ± 0.06	–	0.87 ± 0.04
DEQA	–	0.76 ± 0.06	–
DERA	0.9 ± 0.04	–	–
DAAA	0.9 ± 0.03	–	0.81 ± 0.05
AEAA	1.1 ± 0.05	–	0.91 ± 0.03
AAEA	1.0 ± 0.06	–	–
DEEE	–	0.95 ± 0.05	–

Mutant		P_K/P_Na
	Favre^{^a}	Schlief^{^b}	Sun^{^c}
DEKA	0.03 ± 0.01	0.10 ± 0.03	0.08 ± 0.01
AEKA	0.03 ± 0.03	–	–
DAKA	0.09 ± 0.03	–	–
DEKD	–	0.23 ± 0.05	–
DKEA	–	0.37 ± 0.03	–
DEAA	1.1 ± 0.06	–	0.87 ± 0.04
DEQA	–	0.76 ± 0.06	–
DERA	0.9 ± 0.04	–	–
DAAA	0.9 ± 0.03	–	0.81 ± 0.05
AEAA	1.1 ± 0.05	–	0.91 ± 0.03
AAEA	1.0 ± 0.06	–	–
DEEE	–	0.95 ± 0.05	–

Favre et al., 1996.

Schlief et al., 1996.

Sun et al., 1997.