TABLE I Reversal Potentials of... | Rockefeller University Press

TABLE I

Reversal Potentials of 5-HT–induced Currents in HEK293 Cells Expressing either Wild Type or Truncated 5-HT3A Receptors Are Similar following Reduction of the Bath Solution NaCl Concentration

Extracellular Buffer^{^a}	E2	E3	E4
	mV
5-HT_3A	2 ± 0.7	−15 ± 0.4	−32 ± 0.5
5-HT_3A-glvM3M4	−1 ± 1.5	−12 ± 2.5	−36 ± 4.5
Na⁺ Nernst potential^{^b}	−1	−18	−34
Cl⁻ Nernst potential^{^b}	0.3	18	34

Extracellular Buffer^{^a}	E2	E3	E4
	mV
5-HT_3A	2 ± 0.7	−15 ± 0.4	−32 ± 0.5
5-HT_3A-glvM3M4	−1 ± 1.5	−12 ± 2.5	−36 ± 4.5
Na⁺ Nernst potential^{^b}	−1	−18	−34
Cl⁻ Nernst potential^{^b}	0.3	18	34

Extracellular buffer composition defined in Materials and methods.

Theoretical reversal potential calculated from the Nernst Equation for an ideally selective channel.

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