Bacteria used in this study
| Organism | Strain | Antigens | Role of iNKT in infection | Reference |
| Gram-positive | ||||
| S. pneumoniae | URF918 | GlcDAG, GalGlcDAG | Protective | Burrows et al., 2009; Kawakami et al., 2003 |
| L. monocytogenes | 10403S | N.d. | Protective | Arrunategui-Correa and Kim, 2004 |
| S. aureus | 25923a | N.d. | N.d. | Brigl et al., 2003 |
| Gram-negative | ||||
| P. aeruginosa | D4 | N.d. | Protective | Nieuwenhuis et al., 2002 |
| S. typhimurium | MT110 | N.d. | Not protective | Berntman et al., 2005; Brigl et al., 2003 |
| E. coli | 25922a | N.d. | N.d. | |
| α-Proteobacteria | ||||
| S. capsulata | 14666a | GSL-1 (GlcAGSL) | Protective | Mattner et al., 2005 |
| N. aromaticivorans | 700278a | GSL-1 | Induction of PBC | Mattner et al., 2008 |
| S. yanoikuyae | 51230a | GSL-1 | Protective | Kinjo et al., 2005 |
| Spirochetes | ||||
| B. burgdorferi | N40 | BbGL-II (GalDAG) | Protective | Kinjo et al., 2006; Kumar et al., 2000; Tupin et al., 2008 |
| Mycobacteria | ||||
| M. tuberculosis | H37Rv | PIM4b | Not protective | Behar et al., 1999; Fischer et al., 2004 |
| Organism | Strain | Antigens | Role of iNKT in infection | Reference |
| Gram-positive | ||||
| S. pneumoniae | URF918 | GlcDAG, GalGlcDAG | Protective | Burrows et al., 2009; Kawakami et al., 2003 |
| L. monocytogenes | 10403S | N.d. | Protective | Arrunategui-Correa and Kim, 2004 |
| S. aureus | 25923a | N.d. | N.d. | Brigl et al., 2003 |
| Gram-negative | ||||
| P. aeruginosa | D4 | N.d. | Protective | Nieuwenhuis et al., 2002 |
| S. typhimurium | MT110 | N.d. | Not protective | Berntman et al., 2005; Brigl et al., 2003 |
| E. coli | 25922a | N.d. | N.d. | |
| α-Proteobacteria | ||||
| S. capsulata | 14666a | GSL-1 (GlcAGSL) | Protective | Mattner et al., 2005 |
| N. aromaticivorans | 700278a | GSL-1 | Induction of PBC | Mattner et al., 2008 |
| S. yanoikuyae | 51230a | GSL-1 | Protective | Kinjo et al., 2005 |
| Spirochetes | ||||
| B. burgdorferi | N40 | BbGL-II (GalDAG) | Protective | Kinjo et al., 2006; Kumar et al., 2000; Tupin et al., 2008 |
| Mycobacteria | ||||
| M. tuberculosis | H37Rv | PIM4b | Not protective | Behar et al., 1999; Fischer et al., 2004 |
Description of bacteria used in this study, microbial lipid antigens, if any, described for the respective bacterium, and role of iNKT cells during infection. GlcAGSL, glucuronic acid containing GSL; BbGL-II, B. burgdorferi glycolipid II; GalDAG, galactosyl diacylglycerol; PIM4, phosphatidylinositol mannoside 4; N.d., not described; PBC, primary biliary cirrhosis.
American Type Culture Collection number.
Antigenic activity of this lipid could not be confirmed by some investigators (Kinjo et al., 2006).