Table I.

Bacteria used in this study

Organism Strain Antigens Role of iNKT in infection Reference 
Gram-positive 
S. pneumoniae URF918 GlcDAG, GalGlcDAG Protective Burrows et al., 2009; Kawakami et al., 2003  
L. monocytogenes 10403S N.d. Protective Arrunategui-Correa and Kim, 2004  
S. aureus 25923a N.d. N.d. Brigl et al., 2003  
Gram-negative 
P. aeruginosa D4 N.d. Protective Nieuwenhuis et al., 2002  
S. typhimurium MT110 N.d. Not protective Berntman et al., 2005; Brigl et al., 2003  
E. coli 25922a N.d. N.d.  
α-Proteobacteria 
S. capsulata 14666a GSL-1 (GlcAGSL) Protective Mattner et al., 2005  
N. aromaticivorans 700278a GSL-1 Induction of PBC Mattner et al., 2008  
S. yanoikuyae 51230a GSL-1 Protective Kinjo et al., 2005  
Spirochetes 
B. burgdorferi N40 BbGL-II (GalDAG) Protective Kinjo et al., 2006; Kumar et al., 2000; Tupin et al., 2008  
Mycobacteria 
M. tuberculosis H37Rv PIM4b Not protective Behar et al., 1999; Fischer et al., 2004  

Description of bacteria used in this study, microbial lipid antigens, if any, described for the respective bacterium, and role of iNKT cells during infection. GlcAGSL, glucuronic acid containing GSL; BbGL-II, B. burgdorferi glycolipid II; GalDAG, galactosyl diacylglycerol; PIM4, phosphatidylinositol mannoside 4; N.d., not described; PBC, primary biliary cirrhosis.

a

American Type Culture Collection number.

b

Antigenic activity of this lipid could not be confirmed by some investigators (Kinjo et al., 2006).

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