Multilineage hematopoietic engraftment in primary recipient mice
| Recipient no. | Blood | BM | Spleen | Thymus | ||||||||||||
| B | T | NK | Myeloid | B | T | NK | Myeloid | B | T | NK | Myeloid | CD4−CD8− | CD4+CD8+ | CD4+CD8− | CD8+CD4− | |
| % in gated human CD45+ cells | ||||||||||||||||
| 1 | 44 | 39 | NA | 11 | 48 | 19 | NA | 30 | 78 | 12 | NA | 9 | NA | NA | NA | NA |
| 2 | 67 | 23 | 3 | 4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 3 | 19 | 65 | 5 | 11 | 16 | 42 | 1 | 38 | 29 | 56 | 1 | 15 | 1 | 68 | 25 | 6 |
| 4 | 77 | 5 | 4 | 12 | 51 | 0.1 | 0.2 | 45 | 87 | 1 | 1 | 9 | 2 | 84 | 10 | 4 |
| 5 | 75 | 19 | 2 | 4 | 62 | 1 | 0.3 | 37 | 90 | 7 | 0.7 | 2 | 3 | 80 | 13 | 4 |
| 6 | 56 | 25 | 9 | 9 | 61 | 19 | 1 | 20 | 82 | 4 | 3 | 14 | 2 | 85 | 9 | 4 |
| 7 | 17 | 36 | 31 | 18 | 20 | 4 | 1.5 | 74 | 41 | 39 | 11 | 11 | NA | NA | NA | NA |
| 8 | 59 | 22 | NA | 15 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 9 | 63 | 19 | NA | 14 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 10 | 26 | 60 | 9 | 6 | 42 | 12 | 2 | 43 | 46 | 41 | 7 | 7 | 2 | 69 | 22 | 7 |
| Recipient no. | Blood | BM | Spleen | Thymus | ||||||||||||
| B | T | NK | Myeloid | B | T | NK | Myeloid | B | T | NK | Myeloid | CD4−CD8− | CD4+CD8+ | CD4+CD8− | CD8+CD4− | |
| % in gated human CD45+ cells | ||||||||||||||||
| 1 | 44 | 39 | NA | 11 | 48 | 19 | NA | 30 | 78 | 12 | NA | 9 | NA | NA | NA | NA |
| 2 | 67 | 23 | 3 | 4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 3 | 19 | 65 | 5 | 11 | 16 | 42 | 1 | 38 | 29 | 56 | 1 | 15 | 1 | 68 | 25 | 6 |
| 4 | 77 | 5 | 4 | 12 | 51 | 0.1 | 0.2 | 45 | 87 | 1 | 1 | 9 | 2 | 84 | 10 | 4 |
| 5 | 75 | 19 | 2 | 4 | 62 | 1 | 0.3 | 37 | 90 | 7 | 0.7 | 2 | 3 | 80 | 13 | 4 |
| 6 | 56 | 25 | 9 | 9 | 61 | 19 | 1 | 20 | 82 | 4 | 3 | 14 | 2 | 85 | 9 | 4 |
| 7 | 17 | 36 | 31 | 18 | 20 | 4 | 1.5 | 74 | 41 | 39 | 11 | 11 | NA | NA | NA | NA |
| 8 | 59 | 22 | NA | 15 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 9 | 63 | 19 | NA | 14 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 10 | 26 | 60 | 9 | 6 | 42 | 12 | 2 | 43 | 46 | 41 | 7 | 7 | 2 | 69 | 22 | 7 |
Data shown are the percentage of B (CD19+), T (CD3+ or CD4+CD8+, CD4+CD8−, and CD8+CD4−), NK (CD94+CD3−), and myeloid cells (CD33+ or CD13+) in the human CD45+ cell population in the peripheral blood, BM, spleen, and thymus of NSG mice transplanted with AGM region and yolk sac cells. The recipient identification numbers are the same as in Table II. NA, not assessed.