Table II. High level hematopoietic... | Rockefeller University Press

Table II.

High level hematopoietic repopulation by a single early embryonic HSC

Recipient no.	Tissues transplanted	Time after transplantation	Human CD45⁺ cells in the recipient blood	Human CD45⁺ cells in the recipient BM	Human CD45⁺ cells in the recipient spleen
		mo	%	%	%
1	AGM region	4	29	42	4
2	AGM region	4	9	NA	NA
3	AGM region	4	24	45	31
4	AGM region	7	39	86	87
5	AGM region	7	73	93	93
6	AGM region	7	22	71	75
7	AGM region	8	90	94	96
8	Yolk sac	4.5	7	NA	NA
9	Yolk sac	7.5	56	NA	NA
10	Yolk sac	7.5	34	79	87

Recipient no.	Tissues transplanted	Time after transplantation	Human CD45⁺ cells in the recipient blood	Human CD45⁺ cells in the recipient BM	Human CD45⁺ cells in the recipient spleen
		mo	%	%	%
1	AGM region	4	29	42	4
2	AGM region	4	9	NA	NA
3	AGM region	4	24	45	31
4	AGM region	7	39	86	87
5	AGM region	7	73	93	93
6	AGM region	7	22	71	75
7	AGM region	8	90	94	96
8	Yolk sac	4.5	7	NA	NA
9	Yolk sac	7.5	56	NA	NA
10	Yolk sac	7.5	34	79	87

NSG mice transplanted with HSCs derived from the human AGM region or yolk sac were observed for 4–8 mo. At the end of each experiment, the percentage of human CD45⁺ cells in the recipient peripheral blood, BM, and spleen was assessed by flow cytometry. NA, not assessed as the recipients died.

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