Table I.

SHM frequencies in JH4 introns of GC B cells

 WT K164R Ung K164R × Ung Msh2 K164R × Msh2 
Number of mice 
Number of mutated sequences 234 183 76 90 114 90 
Total mutations 1,083 563 442 290 216 181 
Total bp sequenced 115,695 93,356 39,049 46,008 58,049 45,647 
Mutations/bp (%) 0.9 (0.6–1.5) 0.6 (0.4–0.7) 1.1 (1–1.3) 0.6 (0.6–0.7) 0.4 (0.3–0.4) 0.4 (0.3–0.5) 
 WT K164R Ung K164R × Ung Msh2 K164R × Msh2 
Number of mice 
Number of mutated sequences 234 183 76 90 114 90 
Total mutations 1,083 563 442 290 216 181 
Total bp sequenced 115,695 93,356 39,049 46,008 58,049 45,647 
Mutations/bp (%) 0.9 (0.6–1.5) 0.6 (0.4–0.7) 1.1 (1–1.3) 0.6 (0.6–0.7) 0.4 (0.3–0.4) 0.4 (0.3–0.5) 

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