Histological grading of intestinal inflammation
| Symptom | Characteristics |
| Infiltration of inflammatory cells | |
| 0 | Rare inflammatory cells in the lamina propria |
| 1 | Increased numbers of inflammatory cells, including neutrophils in the lamina propria |
| 2 | Confluence of inflammatory cells extending into the submucosa |
| 3 | Transmural extension of the inflammatory cell infiltrate |
| Infiltration of lamina propria by mononuclear cells | |
| 0 | Normal |
| 1 | Moderate |
| 2 | Great |
| Infiltration of lamina propria by polynuclear cells | |
| 0 | Normal |
| 1 | Moderate |
| 2 | Great |
| Infiltration of epithelium by polynuclear cells | |
| 0 | No infiltration |
| 1 | Surface |
| 2 | Inside the crypt |
| 3 | Cryptic abscess |
| Severity of epithelial damage | |
| 0 | Absence of mucosal damage |
| 1 | Lymphoepithelial lesions |
| 2 | Mucosal erosion/ulceration |
| 3 | Extensive mucosal damage and extension through deeper structures of the bowel wall |
| Surface of epithelial damage | |
| 0 | Normal |
| 1 | Focal |
| 2 | Wide |
| Symptom | Characteristics |
| Infiltration of inflammatory cells | |
| 0 | Rare inflammatory cells in the lamina propria |
| 1 | Increased numbers of inflammatory cells, including neutrophils in the lamina propria |
| 2 | Confluence of inflammatory cells extending into the submucosa |
| 3 | Transmural extension of the inflammatory cell infiltrate |
| Infiltration of lamina propria by mononuclear cells | |
| 0 | Normal |
| 1 | Moderate |
| 2 | Great |
| Infiltration of lamina propria by polynuclear cells | |
| 0 | Normal |
| 1 | Moderate |
| 2 | Great |
| Infiltration of epithelium by polynuclear cells | |
| 0 | No infiltration |
| 1 | Surface |
| 2 | Inside the crypt |
| 3 | Cryptic abscess |
| Severity of epithelial damage | |
| 0 | Absence of mucosal damage |
| 1 | Lymphoepithelial lesions |
| 2 | Mucosal erosion/ulceration |
| 3 | Extensive mucosal damage and extension through deeper structures of the bowel wall |
| Surface of epithelial damage | |
| 0 | Normal |
| 1 | Focal |
| 2 | Wide |