Subsets of IL-7Rα−/− and WT DCs in the thymus of adoptive recipientsa
| IL-7Rα−/− recipients of WT bone marrow cells | pDCs | cDCs | |||
| Origin of cells | Number of thymocytes | Number of DCs | Sirpα+ CD11b− B220+ | Sirpα+ CD11b+ CD8α−/lo | Sirpα− CD11b− CD8αhi |
| x10−6 | x10−3 | % | % | % | |
| WT | 54.3 ± 8.9b | 27 ± 11.1c | 5.7 ± 1.8bc | 6.7 ± 2.8bc | 87.5 ± 7bc |
| IL-7Rα−/− | 0.8 ± 0.3 | 33.4 ± 3.5d | 29.8 ± 0.7d | 67 ± 3.6d | 4.2 ± 1.2d |
| WT control | 93.2 ± 13 | 60.5 ± 12.1 | 38.7 ± 3.7 | 22.2 ± 7.5 | 39.1 ± 7.3 |
| IL-7Rα−/− recipients of WT bone marrow cells | pDCs | cDCs | |||
| Origin of cells | Number of thymocytes | Number of DCs | Sirpα+ CD11b− B220+ | Sirpα+ CD11b+ CD8α−/lo | Sirpα− CD11b− CD8αhi |
| x10−6 | x10−3 | % | % | % | |
| WT | 54.3 ± 8.9b | 27 ± 11.1c | 5.7 ± 1.8bc | 6.7 ± 2.8bc | 87.5 ± 7bc |
| IL-7Rα−/− | 0.8 ± 0.3 | 33.4 ± 3.5d | 29.8 ± 0.7d | 67 ± 3.6d | 4.2 ± 1.2d |
| WT control | 93.2 ± 13 | 60.5 ± 12.1 | 38.7 ± 3.7 | 22.2 ± 7.5 | 39.1 ± 7.3 |