Table I. Demographic comparison among... | Rockefeller University Press

Table I.

Demographic comparison among subject groups

	Control	SLE	T1D
Number of subjects	26	24	25
Average age (yr)	33.8 (22–52)	37.3 (21–55)	38.5 (19–69)
Female (%)^{^a}	0.88	0.88	0.56
Caucasian (%)^{^a}	0.58	0.29	0.92
African-American (%)	0.27	0.42	0.04
Other (%)	0.15	0.29	0.04
Mean κ/λ ratio (CD19⁺)	1.5 (1.1–2.3)	1.8 (1–4)	1.6 (0.8–2.4)
Mean B cell fraction (CD19⁺)	0.11 (0.05–0.19)	0.1 (0.01–0.2)	0.1 (0.02–0.19)
Mean absolute B cell count (per μl)^{^b}	221 ± 126	176 ± 163	190 ± 107

	Control	SLE	T1D
Number of subjects	26	24	25
Average age (yr)	33.8 (22–52)	37.3 (21–55)	38.5 (19–69)
Female (%)^a	0.88	0.88	0.56
Caucasian (%)^a	0.58	0.29	0.92
African-American (%)	0.27	0.42	0.04
Other (%)	0.15	0.29	0.04
Mean κ/λ ratio (CD19⁺)	1.5 (1.1–2.3)	1.8 (1–4)	1.6 (0.8–2.4)
Mean B cell fraction (CD19⁺)	0.11 (0.05–0.19)	0.1 (0.01–0.2)	0.1 (0.02–0.19)
Mean absolute B cell count (per μl)^b	221 ± 126	176 ± 163	190 ± 107

Significant differences were found with respect to gender and race between the T1D and control groups (P < 0.05 and P < 0.01, respectively) as well as between the T1D and SLE groups (P < 0.05 and P < 0.001, respectively).

Absolute B cell counts were obtained by multiplying the WBC count (from the complete blood count) by the percentage of lymphocytes (from the electronic differential) and by the CD19⁺ fraction, and are listed as means ± SD. Absolute B cell counts represent the average of 25 control subjects, 23 SLE patients, and 24 T1D patients, respectively.

[ViewLarge]

Sharing Unavailable