Table I.

Ratio of IgG1a/IgG1b in hybridomas

Genotype
IgG1a/IgG1b
CSR (%)
WT-Sγ1 63:42 100 
ΔSγ1 0:160 
2-SSγ1+ 38:81 31 
2-SSγ1 16:112 
2-SSγ3+ 43:94 30 
2-SSγ3 12:96 
2-Sγ3+ 52:72 47 
2-Sγ3 6:30 13 
Genotype
IgG1a/IgG1b
CSR (%)
WT-Sγ1 63:42 100 
ΔSγ1 0:160 
2-SSγ1+ 38:81 31 
2-SSγ1 16:112 
2-SSγ3+ 43:94 30 
2-SSγ3 12:96 
2-Sγ3+ 52:72 47 
2-Sγ3 6:30 13 

The numbers of IgG1a or IgG1b are indicated. Relative CSR frequency is defined by the ratio of IgG1a- to IgG1-producing hybridomas and is arbitrarily set as 100% for F1 cells (see Materials and methods). The data for WT and 2-SSγ1 were adopted from our previous study (reference 9).

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