Summary of secondary transplant results
| Age of original donor and 24-wk lineage contribution ratio in primary recipient | Proportion of successful secondary transplants |
| Young | |
| Myeloid dominant | 9 of 9 |
| Balanced | 9 of 9 |
| Lymphoid dominant | 2 of 2 |
| Total | 20 of 20 |
| Old | |
| Myeloid dominant | 16 of 26 |
| Balanced | 8 of 11 |
| Lymphoid dominant | 0 of 1 |
| Total | 24 of 38 |
| Age of original donor and 24-wk lineage contribution ratio in primary recipient | Proportion of successful secondary transplants |
| Young | |
| Myeloid dominant | 9 of 9 |
| Balanced | 9 of 9 |
| Lymphoid dominant | 2 of 2 |
| Total | 20 of 20 |
| Old | |
| Myeloid dominant | 16 of 26 |
| Balanced | 8 of 11 |
| Lymphoid dominant | 0 of 1 |
| Total | 24 of 38 |
42–52 wk after transplant, BM was harvested from 20 primary recipients of young LSK48−34−E+150+ cells and 38 primary recipients of old LSK48−34−E+150+ cells as shown in Fig. 3 and injected into pairs of secondary recipients. Shown in the table are the success rates (i.e., one or both secondary recipients with >1% donor contribution to circulating Gr-1+SSChi cells at 24 wk) for secondary transplantations from primary recipients of old and young myeloid-dominant, balanced, and lymphoid-dominant HSCs.