Phenotype of cDCs and pDCs in pancreatic LNs from LCMV-infected Vα14 Ins-NP mice
| Cell surface marker | cDCs (CD11c+120G8−) | pDCs (CD11c+120G8+) | ||||
| Day 0 | Day 6 | Fold change | Day 0 | Day 6 | Fold change | |
| CD80 | 255 ± 20 | 462 ± 11a | 1.81 | 204 ± 36 | 405 ± 18a | 1.98 |
| CD86 | 325 ± 33 | 543 ± 18a | 1.67 | 285 ± 19 | 475 ± 31a | 1.67 |
| CD40 | 240 ± 18 | 470 ± 41a | 1.95 | 125 ± 12 | 350 ± 20a | 2.80 |
| I-Ag7 (MHC class II) | 824 ± 45 | 1,180 ± 37a | 1.43 | 201 ± 43 | 274 ± 51a | 1.36 |
| PD-L1 | 582 ± 23 | 1,056 ± 27a | 1.81 | 219 ± 25 | 738 ± 35a | 3.37 |
| Cell surface marker | cDCs (CD11c+120G8−) | pDCs (CD11c+120G8+) | ||||
| Day 0 | Day 6 | Fold change | Day 0 | Day 6 | Fold change | |
| CD80 | 255 ± 20 | 462 ± 11a | 1.81 | 204 ± 36 | 405 ± 18a | 1.98 |
| CD86 | 325 ± 33 | 543 ± 18a | 1.67 | 285 ± 19 | 475 ± 31a | 1.67 |
| CD40 | 240 ± 18 | 470 ± 41a | 1.95 | 125 ± 12 | 350 ± 20a | 2.80 |
| I-Ag7 (MHC class II) | 824 ± 45 | 1,180 ± 37a | 1.43 | 201 ± 43 | 274 ± 51a | 1.36 |
| PD-L1 | 582 ± 23 | 1,056 ± 27a | 1.81 | 219 ± 25 | 738 ± 35a | 3.37 |
MFI was assessed on DC subsets in pancreatic LNs of Ins-NP Vα14 mice before and 6 d after LCMV infection. Results correspond to means ± SD of values obtained in four independent experiments with three pooled mice per group.
P < 0.05 for day 6 compared with day 0.