Table VI.

Inhibition of HIV-1 infection with NL-LucR.T2A-BaL.ecto by mAbs in intact PBMC and PBMC cell subsets

mAb Target cell populationsa 
 Intact PBMC CD4+ T cells CD4+ T cell-depleted PBMC CD14+ monocytes CD14+ monocyte-depleted PBMC 
 µg/ml µg/ml µg/ml µg/ml µg/ml 
PGN632 0.29 >50 0.31 0.18 >50 
IgG1b12 6.2 4.6 0.57 0.65 5.1 
2G12 0.39 4.6 0.06 0.03 5.0 
4E10 40 41 47 32 42 
mAb Target cell populationsa 
 Intact PBMC CD4+ T cells CD4+ T cell-depleted PBMC CD14+ monocytes CD14+ monocyte-depleted PBMC 
 µg/ml µg/ml µg/ml µg/ml µg/ml 
PGN632 0.29 >50 0.31 0.18 >50 
IgG1b12 6.2 4.6 0.57 0.65 5.1 
2G12 0.39 4.6 0.06 0.03 5.0 
4E10 40 41 47 32 42 
a

Target cell populations are IC80 values

or Create an Account

Close Modal
Close Modal