Effect of SC xenografts on course of disease in overtly diabetic mice
| Number | Mouse ID | Age at onset | Maximum BG before transplantation | BG 1 wk after transplantation | BG 2 wk after transplantation | BG < 250 mg/dl after transplantation | Survival after transplantation |
| wk | mg/dl | mg/dl | d | d | |||
| 1 | A4 | 12 | 447 | 345 | 216 | >106 | >120 |
| 2 | A17 | 12 | 362 | 244 | 143 | >113 | >120 |
| 3 | B8 | 14 | 424 | >500 | >500 | NA | 60 |
| 4 | A32 | 14 | 498 | >500 | >500 | NA | 60 |
| 5 | C13 | 16 | 321 | 216 | 165 | >113 | >120 |
| 6 | B44 | 14 | 390 | 234 | 230 | >113 | >120 |
| 7 | D78 | 16 | 420 | 320 | 211 | >100 | >120 |
| 8 | C25 | 15 | 480 | 289 | 197 | >106 | >120 |
| 9 | B40 | 16 | 420 | 320 | 188 | >106 | >120 |
| 10 | A98 | 14 | 370 | 310 | 206 | >106 | >120 |
| 11 | A23 | 14 | 390 | 238 | 212 | >113 | >120 |
| 12 | C39 | 14 | 402 | 330 | 200 | >106 | >120 |
| 13 | C36 | 16 | 346 | >500 | >500 | NA | 60 |
| 14 | A14 | 14 | 360 | 308 | 488 | NA | 90 |
| 15 | B24 | 14 | 350 | 211 | 192 | >113 | >120 |
| 16 | C12 | 15 | 330 | 225 | 184 | >113 | >120 |
| 17 | A29 | 15 | >500 | 242 | 188 | >113 | >120 |
| 18 | D30 | 15 | >500 | 493 | 227 | >106 | >120 |
| 19 | C50 | 15 | >500 | 375 | 218 | >106 | >120 |
| 20 | B63 | 15 | 470 | 500 | 244 | >106 | >120 |
| 21 | C56 | 15 | >500 | 321 | 201 | >106 | >120 |
| Number | Mouse ID | Age at onset | Maximum BG before transplantation | BG 1 wk after transplantation | BG 2 wk after transplantation | BG < 250 mg/dl after transplantation | Survival after transplantation |
| wk | mg/dl | mg/dl | d | d | |||
| 1 | A4 | 12 | 447 | 345 | 216 | >106 | >120 |
| 2 | A17 | 12 | 362 | 244 | 143 | >113 | >120 |
| 3 | B8 | 14 | 424 | >500 | >500 | NA | 60 |
| 4 | A32 | 14 | 498 | >500 | >500 | NA | 60 |
| 5 | C13 | 16 | 321 | 216 | 165 | >113 | >120 |
| 6 | B44 | 14 | 390 | 234 | 230 | >113 | >120 |
| 7 | D78 | 16 | 420 | 320 | 211 | >100 | >120 |
| 8 | C25 | 15 | 480 | 289 | 197 | >106 | >120 |
| 9 | B40 | 16 | 420 | 320 | 188 | >106 | >120 |
| 10 | A98 | 14 | 370 | 310 | 206 | >106 | >120 |
| 11 | A23 | 14 | 390 | 238 | 212 | >113 | >120 |
| 12 | C39 | 14 | 402 | 330 | 200 | >106 | >120 |
| 13 | C36 | 16 | 346 | >500 | >500 | NA | 60 |
| 14 | A14 | 14 | 360 | 308 | 488 | NA | 90 |
| 15 | B24 | 14 | 350 | 211 | 192 | >113 | >120 |
| 16 | C12 | 15 | 330 | 225 | 184 | >113 | >120 |
| 17 | A29 | 15 | >500 | 242 | 188 | >113 | >120 |
| 18 | D30 | 15 | >500 | 493 | 227 | >106 | >120 |
| 19 | C50 | 15 | >500 | 375 | 218 | >106 | >120 |
| 20 | B63 | 15 | 470 | 500 | 244 | >106 | >120 |
| 21 | C56 | 15 | >500 | 321 | 201 | >106 | >120 |
Severely diabetic recipient mice received 2 × 107 encapsulated SCs, to be monitored for blood glucose (BG) concentrations over time and survival. 10 mice (not indicated in the table) became stably normoglycemic (blood glucose < 200 mg/dl).