Antigen specificities of autoreactive T cell lines
| TT | PPD | Flu | MelanA | |
| Donor 1 | + | n.d. | + | n.d. |
| Donor 2 | − | ++ | ++ | ++ |
| Donor 3 | ++ | n.d. | + | + |
| Donor 4 | + | + | + | − |
| Donor 5 | n.d. | n.d. | + | n.d. |
| TT | PPD | Flu | MelanA | |
| Donor 1 | + | n.d. | + | n.d. |
| Donor 2 | − | ++ | ++ | ++ |
| Donor 3 | ++ | n.d. | + | + |
| Donor 4 | + | + | + | − |
| Donor 5 | n.d. | n.d. | + | n.d. |
CCR6+ T cells that had completely lost CFSE labeling after stimulation with autologous DCs and anti–IL-10 antibodies for 7 d were sorted, expanded with recombinant IL-2, and tested for cytokine production (TNF, IFN-γ, or IL-2) after restimulation with autologous monocytes in the absence or presence of TT, purified protein derivate (PPD), influenza hemagglutinin (Flu), or MelanA. −, cytokine responses <0.1% over control; +, cytokine responses between 0.1 and 1% over control; and ++, cytokine responses >1% over control. n.d., not done.