Number of T cells interacting with mDCs, expressing CCR6, FOXP3, or IL-10 in human spleen sections
| T cell area | Total CD3+ | CD3+ close to DCs | Total CCR6+ | CCR6+ close to DCs | Total FOXP3+ | CD3+ IL-10+ | FOXP3+ IL-10+ | CCR6+ IL-10+ | |
| 1A | 137 | 42 | 21 | 14 | 5 | 13 | 1 | 4 | |
| 1B | 124 | 38 | 17 | 12 | 4 | 11 | 0 | 2 | |
| 2A | 175 | 61 | 35 | 23 | 12 | 15 | 1 | 5 | |
| 2B | 225 | 95 | 63 | 37 | 8 | 22 | 2 | 7 | |
| 3A | 105 | 31 | 14 | 11 | 3 | 8 | 0 | 3 | |
| 3B | 92 | 28 | 9 | 7 | 4 | 9 | 0 | 1 | |
| 4A | 80 | 26 | 7 | 6 | 3 | 7 | 0 | 2 | |
| 4B | 76 | 20 | 7 | 5 | 5 | 5 | 0 | 3 | |
| 5A | 119 | 42 | 13 | 9 | 6 | 11 | 0 | 2 | |
| 5B | 85 | 31 | 10 | 4 | 3 | 6 | 0 | 1 | |
| Mean | 122 ± 47 | 41 ± 22 | 20 ± 17 | 13 ± 10 | 5 ± 3 | 11 ± 5 | 0.4 ± 0.7 | 3 ± 2 | |
| % | 34 (CD3+) | 16 (CD3+) | 66 (CCR6+) | 4 (CD3+) | 9 (CD3+) | 4 (IL-10+) | 28 (IL-10+) |
| T cell area | Total CD3+ | CD3+ close to DCs | Total CCR6+ | CCR6+ close to DCs | Total FOXP3+ | CD3+ IL-10+ | FOXP3+ IL-10+ | CCR6+ IL-10+ | |
| 1A | 137 | 42 | 21 | 14 | 5 | 13 | 1 | 4 | |
| 1B | 124 | 38 | 17 | 12 | 4 | 11 | 0 | 2 | |
| 2A | 175 | 61 | 35 | 23 | 12 | 15 | 1 | 5 | |
| 2B | 225 | 95 | 63 | 37 | 8 | 22 | 2 | 7 | |
| 3A | 105 | 31 | 14 | 11 | 3 | 8 | 0 | 3 | |
| 3B | 92 | 28 | 9 | 7 | 4 | 9 | 0 | 1 | |
| 4A | 80 | 26 | 7 | 6 | 3 | 7 | 0 | 2 | |
| 4B | 76 | 20 | 7 | 5 | 5 | 5 | 0 | 3 | |
| 5A | 119 | 42 | 13 | 9 | 6 | 11 | 0 | 2 | |
| 5B | 85 | 31 | 10 | 4 | 3 | 6 | 0 | 1 | |
| Mean | 122 ± 47 | 41 ± 22 | 20 ± 17 | 13 ± 10 | 5 ± 3 | 11 ± 5 | 0.4 ± 0.7 | 3 ± 2 | |
| % | 34 (CD3+) | 16 (CD3+) | 66 (CCR6+) | 4 (CD3+) | 9 (CD3+) | 4 (IL-10+) | 28 (IL-10+) |
Cells staining positive for CD3, CCR6, IL-10, or FOXP3 in the vicinity or not of CD11c mDCs were counted in two T cell areas (A and B) in five different spleen samples (1–5), and the mean numbers, percentages, and standard deviations were calculated.
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