Encephalitogenicity in spontaneous EAE is dependent on T-bet
| Incidence of EAE | Mean day of onseta | Maximum clinical score | Peak mean clinical scorea | |
| siRNA-NS | 5/8 (62.5%) | 10.8 ± 1.1 | 2 | 1.1 ± 1 |
| siRNA-Tbet | 0/8 (0%) | NA | NA | NA |
| Incidence of EAE | Mean day of onset | Maximum clinical score | Peak mean clinical score | |
| siRNA-NS | 5/8 (62.5%) | 10.8 ± 1.1 | 2 | 1.1 ± 1 |
| siRNA-Tbet | 0/8 (0%) | NA | NA | NA |
NA, not applicable.
Mean day of onset and peak mean clinical score were determined for the five mice that developed EAE.
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