Table III.

Encephalitogenicity in spontaneous EAE is dependent on T-bet

 Incidence of EAE Mean day of onseta Maximum clinical score Peak mean clinical scorea 
siRNA-NS 5/8 (62.5%) 10.8 ± 1.1 2 1.1 ± 1 
siRNA-Tbet 0/8 (0%) NA NA NA 
 Incidence of EAE Mean day of onseta Maximum clinical score Peak mean clinical scorea 
siRNA-NS 5/8 (62.5%) 10.8 ± 1.1 2 1.1 ± 1 
siRNA-Tbet 0/8 (0%) NA NA NA 

NA, not applicable.

a

Mean day of onset and peak mean clinical score were determined for the five mice that developed EAE.

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