Table II.

Summary of percentage tumor-free mice at endpoint of experiment described in Fig. 2 

Treatment group Tumor-free /total mice replicate 1 Tumor-free /total mice replicate 2 Combined percent tumor free Statistical significance 
versus 6 × 106 versus 0 versus naive 
103 11 / 14 12 / 16 77% P < 0.01 P < 0.001a P < 0.001a 
105 11 / 15 14 / 16 81% P < 0.01 P < 0.001a P < 0.001a 
106 10 / 15 9 / 16 52%  P < 0.05 P < 0.001a 
6 × 106 5 / 12 5 / 15 37%    
0 (no pmel) 6 / 14 2 / 15 28%    
Naive 1 / 10 3 / 15 16%    
Treatment group Tumor-free /total mice replicate 1 Tumor-free /total mice replicate 2 Combined percent tumor free Statistical significance 
versus 6 × 106 versus 0 versus naive 
103 11 / 14 12 / 16 77% P < 0.01 P < 0.001a P < 0.001a 
105 11 / 15 14 / 16 81% P < 0.01 P < 0.001a P < 0.001a 
106 10 / 15 9 / 16 52%  P < 0.05 P < 0.001a 
6 × 106 5 / 12 5 / 15 37%    
0 (no pmel) 6 / 14 2 / 15 28%    
Naive 1 / 10 3 / 15 16%    

Endpoint was day 104 (replicate 1) and day 131 (replicate 2) post-tumor challenge. Statistical significance was calculated for combined experiment.

a

Indicates values remaining significant after correction for multiple comparisons.

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