Table I.

KD values for the binding of Vps74 and GOLPH3 to phosphoinositides

Protein PtdIns4P PtdIns3P PtdIns5P PtdIns(4,5)P2 
Vps74 8.9 ± 0.3 µM >50 µM >50 µM >50 µM 
GOLPH3 2.6 ± 0.2 µM 10.2 ± 0.5 µM ∼25 µM ∼25 µM 
Protein PtdIns4P PtdIns3P PtdIns5P PtdIns(4,5)P2 
Vps74 8.9 ± 0.3 µM >50 µM >50 µM >50 µM 
GOLPH3 2.6 ± 0.2 µM 10.2 ± 0.5 µM ∼25 µM ∼25 µM 

Values were determined from SPR (Biacore) analysis.

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