Table I.

Clinical characteristics of patients and controls


Overall CHB
Low viral load
High viral load
Healthy donor
n 58 35 23 28 
Median age (range) 35 (23–69) 35 (23–69) 36 (23–63) 28 (22–44) 
Sex (M:F ratio) % male (41:17) 70% (25:10) 71% (16:7) 70% (14:14) 50% 
Median serum HBVDNA (IU/ml; range) 250,000     (BLQ–340 × 1061,400     (BLQ–945700) 78 × 106(1.1 × 106–340 × 106
Median ALT (IU/liter; range) 50 (21–498) 36 (21–498) 73 (24–363) 
HBeAg status (% positive) 11% 10% 87% 

Overall CHB
Low viral load
High viral load
Healthy donor
n 58 35 23 28 
Median age (range) 35 (23–69) 35 (23–69) 36 (23–63) 28 (22–44) 
Sex (M:F ratio) % male (41:17) 70% (25:10) 71% (16:7) 70% (14:14) 50% 
Median serum HBVDNA (IU/ml; range) 250,000     (BLQ–340 × 1061,400     (BLQ–945700) 78 × 106(1.1 × 106–340 × 106
Median ALT (IU/liter; range) 50 (21–498) 36 (21–498) 73 (24–363) 
HBeAg status (% positive) 11% 10% 87% 

BLQ, DNA positive but below limit of quantification, i.e., <50 IU/ml.

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