Table I. IgH SHM analysis of fetal... | Rockefeller University Press

Table I.

IgH SHM analysis of fetal spleen B cells

B cells	Total unique sequences	Mutated sequences^{^a}	% of mutation frequency^{^b}	Mutation range
Donor 1 IgD⁺CD27⁻	11	0	–	–
Donor 1 IgD⁺CD27⁺	18	3 (17%)	2.3	5–7
Donor 2 IgD⁺CD27⁺	19	3 (16%)	2.7	5–11
Donor 3 IgD⁺CD27⁺	29	6 (21%)	2.4	3–12

B cells	Total unique sequences	Mutated sequences^a	% of mutation frequency^b	Mutation range
Donor 1 IgD⁺CD27⁻	11	0	–	–
Donor 1 IgD⁺CD27⁺	18	3 (17%)	2.3	5–7
Donor 2 IgD⁺CD27⁺	19	3 (16%)	2.7	5–11
Donor 3 IgD⁺CD27⁺	29	6 (21%)	2.4	3–12

Only unique rearrangements were considered for analysis. Sequences scored as mutated contained three or more mutations (≥1% mutation frequency). In brackets is the frequency of mutated sequences among all sequences.

The percentage of point mutations among the total number of sequenced nucleotides of mutated sequences.

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