Hemodynamic parameters (mean ± SEM of diameter, centerline velocity, shear rate, and WBC) of cremaster muscle venules in ST3Gal-IV−/−, CXCR2bm−/−, and WT control mice
. | . | Mice . | Venules . | Diameter . | Blood flow velocity . | Shear rate . | WBC . |
|---|---|---|---|---|---|---|---|
| (n) | (n) | (μm) | (μm/s) | (1/s) | (/μl) | ||
| Cremaster venules in trauma-induced inflammation | ST3Gal-IV −/− | 13 | 58 | 30 ± 1 | 2,800 ± 200 | 2,400 ± 200 | 5,500 ± 600 |
| WT | 13 | 37 | 32 ± 1 | 3,100 ± 200 | 2,500 ± 200 | 5,600 ± 800 | |
| n.s. | n.s. | n.s. | n.s. | ||||
| Chemokine-treated cremaster venules in trauma-induced inflammation | ST3Gal-IV−/− | 10 | 19 | 31 ± 1 | 2,000 ± 200 | 1,700 ± 100 | 5,700 ± 700 |
| CXCR2bm−/− | 5 | 5 | 31 ± 3 | 1,600 ± 100 | 1,500 ± 300 | 4,800 ± 100 | |
| WT | 19 | 30 | 30 ± 1 | 2,300 ± 200 | 1,900 ± 200 | 6,300 ± 500 | |
| n.s. | n.s. | n.s. | n.s. | ||||
| Cremaster venules in TNF-α–induced inflammation | ST3Gal-IV−/− | 16 | 90 | 30 ± 1 | 2,300 ± 100 | 1,900 ± 100 | 3,400 ± 500 |
| CXCR2bm−/− | 8 | 76 | 31 ± 1 | 1,800 ± 110 | 1,500 ± 120 | 2,600 ± 200 | |
| WT | 16 | 67 | 32 ± 1 | 2,100 ± 100 | 1,700 ± 100 | 2,800 ± 400 | |
| n.s. | n.s. | n.s. | n.s. |
. | . | Mice . | Venules . | Diameter . | Blood flow velocity . | Shear rate . | WBC . |
|---|---|---|---|---|---|---|---|
| (n) | (n) | (μm) | (μm/s) | (1/s) | (/μl) | ||
| Cremaster venules in trauma-induced inflammation | ST3Gal-IV −/− | 13 | 58 | 30 ± 1 | 2,800 ± 200 | 2,400 ± 200 | 5,500 ± 600 |
| WT | 13 | 37 | 32 ± 1 | 3,100 ± 200 | 2,500 ± 200 | 5,600 ± 800 | |
| n.s. | n.s. | n.s. | n.s. | ||||
| Chemokine-treated cremaster venules in trauma-induced inflammation | ST3Gal-IV−/− | 10 | 19 | 31 ± 1 | 2,000 ± 200 | 1,700 ± 100 | 5,700 ± 700 |
| CXCR2bm−/− | 5 | 5 | 31 ± 3 | 1,600 ± 100 | 1,500 ± 300 | 4,800 ± 100 | |
| WT | 19 | 30 | 30 ± 1 | 2,300 ± 200 | 1,900 ± 200 | 6,300 ± 500 | |
| n.s. | n.s. | n.s. | n.s. | ||||
| Cremaster venules in TNF-α–induced inflammation | ST3Gal-IV−/− | 16 | 90 | 30 ± 1 | 2,300 ± 100 | 1,900 ± 100 | 3,400 ± 500 |
| CXCR2bm−/− | 8 | 76 | 31 ± 1 | 1,800 ± 110 | 1,500 ± 120 | 2,600 ± 200 | |
| WT | 16 | 67 | 32 ± 1 | 2,100 ± 100 | 1,700 ± 100 | 2,800 ± 400 | |
| n.s. | n.s. | n.s. | n.s. |
n.s., nonsignificant (P > 0.05).