Table IV.

GCR rates in mutants with seven copies of ARSH4

Strain Relevant genotype GCR rates (×10−10
RDK3615 WT 3.5 (1)a 
RDK6307 sit1∷control DNA <4.0 (1)b 
RDK6308 sit1∷7xARSH4 13.9 (4) 
RDK6311 mre11Δ sit1∷control DNA 2,963 (847) 
RDK6312 mre11Δ sit1∷7xARSH4 12,539 (3,580) 
Strain Relevant genotype GCR rates (×10−10
RDK3615 WT 3.5 (1)a 
RDK6307 sit1∷control DNA <4.0 (1)b 
RDK6308 sit1∷7xARSH4 13.9 (4) 
RDK6311 mre11Δ sit1∷control DNA 2,963 (847) 
RDK6312 mre11Δ sit1∷7xARSH4 12,539 (3,580) 

Numbers in parentheses indicate fold increase over WT. The GCR rates are shown as events per generation.

a

Data from Chen and Kolodner (1999).

b

GCR rate could not be accurately calculated because GCRs were not detected in a large enough proportion of the cultures.

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