Reduced Cdc28 activity does not affect non-GCR mutation rates
| Relevant genotype | Hom+ rate (×10−8) | Lys+ rate (×10−8) | Canr rate (×10−7) |
| WT | 1.4 (1.2–1.5) | 1.9 (1.4–2.7) | 3.6 (3.1–5.2) |
| cdc28-5M | 1.2 (0.8–1.6) | 1.8 (1.6–2.5) | 2.3 (1.9–5.8) |
| msh2Δ | 670.2 (405.9–832.8) | 62.1 (50.8–99.0) | 34.6 (16.6–48.8) |
| msh2Δ cdc28-5M | 967.7 (505.4–1,730.9) | 55.3 (45.1–73.6) | 39.3 (31.4–67.6) |
| Relevant genotype | Hom+ rate (×10−8) | Lys+ rate (×10−8) | Canr rate (×10−7) |
| WT | 1.4 (1.2–1.5) | 1.9 (1.4–2.7) | 3.6 (3.1–5.2) |
| cdc28-5M | 1.2 (0.8–1.6) | 1.8 (1.6–2.5) | 2.3 (1.9–5.8) |
| msh2Δ | 670.2 (405.9–832.8) | 62.1 (50.8–99.0) | 34.6 (16.6–48.8) |
| msh2Δ cdc28-5M | 967.7 (505.4–1,730.9) | 55.3 (45.1–73.6) | 39.3 (31.4–67.6) |
Numbers in parentheses indicate confidence intervals. The mutation rates are shown as events per generation.