Table III. V H 6 repertoire analysis of... | Rockefeller University Press

Table III.

V_H6 repertoire analysis of the splenic B cell subsets of an 8-mo-old child

Donor	B cell subset	Transcripts	Number of peaks analyzed^{^a}	Total number of sequences	Number of different VDJ junctions	Clonal diversity^{^b}	P value^{^c}
						%
D3	IgD⁺CD27⁺	V_H6 μ	4	68	58	85
	Naives	V_H6 μ	3	56	36	64
	IgD⁻CD27⁺ (switched + GC)	V_H6 γ	3	50	12	24	7 × 10⁻¹¹
	CD38⁺CD24⁻ (GC)	V_H6 μ	3	55	8	14.5	2 × 10⁻¹⁴
	CD38⁺CD24⁻ (GC)		V_H6 γ	4	76	5	6.5	10⁻²⁰

Donor	B cell subset	Transcripts	Number of peaks analyzed^a	Total number of sequences	Number of different VDJ junctions	Clonal diversity^b	P value^c
						%
D3	IgD⁺CD27⁺	V_H6 μ	4	68	58	85
	Naives	V_H6 μ	3	56	36	64
	IgD⁻CD27⁺ (switched + GC)	V_H6 γ	3	50	12	24	7 × 10⁻¹¹
	CD38⁺CD24⁻ (GC)	V_H6 μ	3	55	8	14.5	2 × 10⁻¹⁴
	CD38⁺CD24⁻ (GC)		V_H6 γ	4	76	5	6.5	10⁻²⁰

The peaks that were analyzed are identified by an asterisk in Fig. 2.

Number of different VDJ among all sequences.

Statistical significance (see Materials and methods) of differences in clonal diversity between IgD⁺CD27⁺ and IgD⁻CD27⁺ or GC cells from the same donor.

[ViewLarge]

Sharing Unavailable